目的:研究C/EBPβ蛋白在新疆维吾尔族妇女子宫颈鳞癌组织中的表达及临床意义。方法:采用免疫组织化学S-P法对38例子宫颈鳞癌组织、28例慢性子宫颈炎组织中C/EBPβ蛋白的表达进行检测。结果:新疆维吾尔族妇女子宫颈鳞癌组织与慢性子宫颈炎C/EBPβ蛋白的表达无显著性差异(P〉0.05);在不同病理分级的肿瘤组织中C/EBPβ蛋白的表达有显著性差异(P〈0.05)。结论:C/EBPβ蛋白表达可能与新疆维吾尔族子宫颈鳞癌不同病理分级相关。
Objective:To explore the expression and clinical significance of C/EBPβ protein with cervical squamous cell carcinoma of Uigur women in Xinjiang. Methods: Immunohistochemistry S-P method was used to detect the expressions of C/EBPβ in 38 cervical squamous cell carcinoma of Uigur women and 28 cervical chronic cervicitis of Uigur women. Results: There was no significant difference in the expressions of C/EBPβ protein between cervical squamous cell carcinoma and cervical chronic cervicitis in Xinjiang's Uigur women (P 〉 0.05);In addition, the expression of C/EBPβ were positive correlated with the hierarchical pathology of the cervical squamous cell carcinoma of Uigur women (P〈0.05). Conclusion: C/EBPβ gene may be associated with the hierarchical pathology of the cervical squamous cell carcinoma of Uigur women.