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中文摘要：
本项目集成并发展细胞、亚细胞层面上生命活动纳米表征相关的生物纳米技术，高灵敏、高选择性地对细胞生长、细胞识别以及细胞内生物分子相互作用等重要生命活动进行纳米表征，对活细胞内与细胞重大生命活动密切相关的蛋白质、核酸等生物分子进行实时、动态观测，为揭示细胞生长、细胞识别以及细胞内生物分子相互作用的规律和机制提供重要信息，并为探索生命奥秘、重大疾病发生发展机制及其治疗提供技术平台。这是一项对细胞生命活动
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期刊论文
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期刊论文
Atomic force microscopy investigation of the characteristic effects of silver ions on Escherichia co
Noninvasive monitoring of intracellular pH change induced by drug stimulation using silica nanoparti
Sensitive fluorescence detection of nucleic acids based on isothermal circular strand-displacement p
Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane
protei
Pyrene-Excimer Probes Based on the Hybridization Chain Reaction
for the Detection of Nucleic Acids i
Electrochemical Detection of Thrombin Based on Aptamer and Ferrocenylhexanethiol Loaded Silica
Nanoc
On-chip oligonucleotide ligation assay using one-dimensional microfluidic beads array for the detect
Telomerase catalyzed fluorescent probes for sensitive protein profiling based on one-dimensional mic
Rhodamine B isothiocyanate doped silica-coated fluorescent nanoparticles (RBITC-DSFNPs)–based biopro
Preparation of luminescent Cy5 doped core-shell SFNPs and its application as a near-infrared fluores
Identification of liver cancer cells in a mixed cell system using galactose-conjugated fluorescent n
Electrochemical detection of nicotinamide adenine dinucleotide based on molecular beacon-like DNA an
Electrochemical biosensors for detection of point mutation based on surface ligation reaction and ol
Barbated Skullcup herb extract-mediated biosynthesis of gold nano-particles andits primary applicati
Fluorescent Nanoparticle-Based Indirect Immunofluorescence Microscopy for Detection of Mycobacterium
A novel molecular beacon based bioassay for highly sensitive and selective detection of NAD+ and the
Chemical etching with tetrafluoroborate: a facile method for resizing of CdTe nanocrystals under mil
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