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虫草及相关真菌的次生代谢产物及其活性
  • 期刊名称:菌物学报, 26(4), 607-632, 2007
  • 时间:0
  • 分类:Q939.5[生物学—微生物学]
  • 作者机构:[1]安徽农业大学安徽省微生物防治重点实验室,合肥230036
  • 相关基金:国家自然科学基金项目(No.30570189);安徽省自然科学基金项目(No.00042425);安徽高校自然科学研究重点项目(No.DT200708).
  • 相关项目:虫生真菌中生物活性物质高通量筛选和鉴定研究
中文摘要:

全面系统地总结了目前在虫草及相关真菌中次生代谢产物研究方面的最新成果,发现目前在虫草及其密切相关的虫生真菌中共报道272个有具体结构的化合物,其活性涉及杀虫、抗癌、抗菌、免疫调节和抗疟原虫等多方面。这些化合物主要来源于20余种虫草、虫草无性型或与虫草密切相关的虫生真菌。虽然近年来有关虫草中生物活性代谢物的研究受到世界各国广泛关注,但仍有90%以上虫草及相关虫生真菌种类中尚无任何具体成分的研究报道,因此有关研究尚需要进一步深入。

英文摘要:

The researches on secondary metabolites from Cordyceps and its related fungi were reviewed. There are 272 compounds with activities of pesticide, anticancer, anti-microbes, immune modulation, anti-plasmodium and so on have been reported. These compounds mainly originated from more than 20 species of Cordyceps and their anamorphs and related fungi. The researches concerning bioactive metabolites from Cordyceps have attracted scientists' attention in various countries of the world. However, there are still more than 90% of the total known species of Cordyceps and their related fungi needing investigation of their bioactive compounds.

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