中文摘要：

从一株南海海洋链霉菌属放线菌195-02中分离得到8个化合物,利用波谱技术确定其结构分别为对羟基苯腈（1）、2-甲基-3-呋喃甲酸（2）、2-呋喃甲酸（3）、环（苯丙-苯丙）二肽（4）、环（亮-异亮）二肽（5）、烟酸（6）、吲哚-3-乙酸（7）和邻苯二甲酸二（2-乙基己基）酯（8）。化合物1、3、8为首次从链霉菌属中分离得到,化合物4～7为首次从海洋放线菌中分离得到。活性测试表明化合物4和5在浓度为50μg/ml时,对喉癌细胞hep2抑制率分别为51%和47%,对肝癌细胞hepG2抑制率分别为40%和31%。

英文摘要：

The metabolites of a marine streptomyces sp.actinomycete（No.195-02） were studied and eight compounds were isolated from the fermentation liquid.structures were elucidated by spectroscopy methods as p-hydroxy-benzonitrile（1）,2-methyl-furan-3-carboxylic acid（2）,furan-2-carboxylic acid（3）,cyclo（Phe-Phe）（4）,cyclo（Leu-Ileu）（5）,nicotinic acid（6）,2-（1H-indol-3-yl） acetic acid（7） and bis（2-ethylhexyl） phthalate（8）.The compounds 1、3 and 8 were firstly isolated from Streptomyces sp.,compounds 4～7 were firstly found from marine actinomycetes.Coumpouds 4 and 5 evidently inhibited the growth of cancer cell lines hepG2 and hep2 at the concentration of 50μg/ml.