目的:对湛江红树林秋茄内生真菌ZZF13和从Mia Po,HongKong的Kandelia candel(endophyte)的树皮分离得到的Guignardia sp.4382的次级代谢产物进行研究。方法:利用硅胶柱层析法进行分离,利用IR、MS、NMR等现代波谱分析方法进行鉴定。结果:从菌丝体中分离得到4个次级代谢产物为Bacillosporin C(1)、5-carboxymellein(2)、5-methylmellein(3)、1-(2,6-二羟基)苯丁酮(4)。结论:化合物2、3、4均首次从Guignardia sp.海洋真菌中得到。
Objective:The secondary metabolitcs of the fungus ZZF13 isolated from the leaves of the mangrove sample Kandelia candel in Zhanjiang and Guignardia sp. 4382 isolated from bark of Kandelia candel (endophyte) of Mai Po, Hong Kong were studied. Methods:The compounds were is olated by siliga gel, and their structures were identified by IR, MS and NMR. Results: Four compounds were isolated from the culture of this strain. Their structures were identified as Bacillpsporin C (1), 5-carboxymellein (2), 5- methylmellein (3) and 1- (2,6-dihydroxyphenyl) butanone (4). Conclusion : The compounds 2 - 4 are isolated from the Guignardia sp. of Marine fungi for the first time.