目的观察补肾活脑汤治疗急性脑梗死的临床疗效、神经功能缺损评分、血液流变学及血脂变化。方法将60例急性脑梗死患者随机分为2组。治疗组30例应用补肾活脑汤治疗,对照组应用尼莫地平片治疗。2组均14d为1个疗程,2个疗程后观察临床疗效,治疗前后神经功能缺损评分、血液流变学及血脂变化情况。结果治疗组总有效率90.0%,对照组总有效率63.3%,2组比较差异有统计学意义(P〈0.05),治疗组疗效优于对照组。2组治疗后神经功能缺损评分、血液流变学指标(全血黏度、血浆黏度、红细胞比容)以及血脂指标(总胆固醇、甘油三酯)较本组治疗前均有降低,且治疗组下降明显优于对照组(P〈0.05)。结论补肾活脑汤治疗怠性脑梗死疗效确切.且能降低血液流变晕及血脂指标。
Objective To observe the curative effects of Bushenhuonao decoction on patients with acute cerebral infarction. Methods Sixty patients with acute cerebral infarction were randomly divided into 2 groups. The patients are treated by Bushenhuonao decoction in the treatment group, and the others are treated by Nimedipine tablet in the control group. In both groups, two courses of treatment are given, and each course has two weeks. The change of neurologic impairment score, the hemorheology and the blood lipid are observed before and after treatment. Results The total effective rate of the treatment group is 90.0% and of the control group is 63.3%. There was significant difference between the two groups on the total effective rate ( P 〈 0.05 ). The treatment group was better than the control group. The neurologic impairment score, indices of the hemorheology and the blood lipid in both groups, in- cluding whole blood viscosity, hematokrit, plasma specific viscosity, whole cholesterol and triglyceride, were decreased after treatment. And the indices of the treatment group decreased more than that of the control group ( P 〈 0.05). Conclusion Bushenhuonao decoction has definite effect on acute cerebral infarction, and can decrease the indexes of the hemorheology and the blood lipid.