位置：成果数据库 > 期刊 > 期刊详情页
动物转基因技术研究新进展及其在牛育种上的应用
  • ISSN号：1001-9111
  • 期刊名称：《中国牛业科学》
  • 时间：0
  • 分类：S823.2[农业科学—畜牧学;农业科学—畜牧兽医]
  • 作者机构：[1]西北农林科技大学动物科技学院,陕西省农业分子生物学重点实验室,陕西杨凌712100
  • 相关基金：国家自然科学基金（编号：30972080）; 国家科技支撑计划项目（编号：2008BADB2B03-19）; 农业部肉牛产业体系项目（编号：CARS-38）; 国家转基因专项子课题（编号：2009ZX08009-157B 2008ZX08007-002 2009ZX08007-005B-07）项目资助
作者： 黄永震[1], 贺花[1], 陈宏[1]
关键词： 动物转基因技术, 转基因效率, 转基因精确调控, Transgenic Animals, Transgenic Efficiency, Precise Control of Transgenic
中文摘要：

动物转基因技术已应用于生命科学的各个领域,尤其在研究基因功能、转基因动物育种（抗病育种和提高生产性能）、治疗人类疾病（生产药用蛋白、干细胞治疗和种器官移植）等方面得到了广泛的应用。本文从转基因技术的历史和发展状况入手,简要介绍了几种传统的转基因技术方法,重点综述了近几年为提高转基因效率和转基因精确调控的一些新技术。另外,本文就转基因技术在牛育种方面的研究现状,以及对转基因技术在牛新品种培育和生物制药等领域的应用和前景进行了综述。

英文摘要：

Transgenic animals have been applied to all areas of life sciences.It has comprehensive application especially in the bioreactor,drug screening,xenotransplantation,improved varieties and improved production performance of animals and other aspects.In this paper,we described the history of the transgenic technology and the state of the development,several traditional methods of transgenic technology was introduced,some new transgenic technologies of focus on improve transgenic efficiency and precise control in recent years.In addition,research status of transgenic technology in cattle breeding and the application and development prospect of cultivate new varieties by transgenic technology in cattle breeding and biopharmaceutical application and prospect and other fields of research in the future.

同期刊论文项目
黄牛重要功能基因拷贝数变异（CNV）的筛选和功能鉴定
期刊论文 68 获奖 6
同项目期刊论文
Haplotype combination of SREBP-1c gene sequence variants is associated with growth traits in cattle
SNPs in the coding region of bovine MGAT2 gene are associated with body weight and weight gain
Polymorphism in GHRH gene and its association with growth traits in Chinese native cattle
Exploring polymorphisms and potential application roles of the bovine Nfix gene in breeding
Sequence variants in the bovine PRDM16 gene associated with body weight in Chinese cattle breeds
郏县红牛跨膜蛋白18基因(TMEM18)SNPs检测及其与生长性状的关联分析
牛血管生成素样蛋白4基因(ANGPTL4)编码区SNPs检测及其与南阳牛生长性状的相关性
Two novel single nucleotide polymorphisms (SNPs) and 4-bp deletion mutation of RBP4 gene in Chinese
Effects of ghrelin gene genotypes on the growth traits in Chinese cattle
A new insight into cattle's maternal origin in six Asian countries
A dual color fluorescent reporter system for the real time detection of promoter activity
The chemokine receptor 1 gene polymorphism and its association with Somatic Cell Score and milk prod
Haplotype combination of the bovine INSIG1 gene sequence variants and association with growth traits
Single Nucleotide Polymorphism (SNP) Analysis of orexin Gene 5 '; Regulatory Region in Chinese Indig
Sequence variants in the bovine nucleophosmin 1 gene, their linkage and their associations with body
Polymorphisms identification and associations of KLF7 gene with cattle growth traits
The peroxisome proliferators-ativated receptor gamma (PPARG) gene polymorphisms and associations wit
Association analysis between variants in bovine NPY gene and growth traits in Nanyang cattle (Bos to
Analysis of the genetic variation of vascular endothelial growth factor gene in three Chinese indige
A novel missense mutation of bovine lipase maturation factor 1 (LMF1) gene and its association with
The polymorphisms of bovine PCSK1 gene and their associations with growth traits
Five novel SNPs of the bovine LHX4 gene and their association with growth traits in native Chinese c
The polymorphisms of bovine VEGF gene and their associations with growth traits in Chinese cattle
Two Novel Coding SNPs of SREBP1c Gene are Associated with Body Weight and Average Daily Gain in Bovi
Novel 12-bp deletion in the coding region of the bovine NPM1 gene affects growth traits
A large indel mutation of the bovine ADD1/SREBP1c gene and its effects on growth traits in some nati
Allelic Polymorphism Detected in the Bovine FTO Gene
The polymorphisms of bovine melanocortin-3 receptor pseudogene
Novel mutation in TGA stop-codon of bovine SIX6 gene
Polymorphism of DLK1 and CLPG gene and their association with phenotypic traits in Chinese cattle
牛POMC基因多态性及其与南阳牛生长性状的相关分析
An efficient and rapid method for gene cloning from eukaryotic genomic DNA using overlap-PCR: With a
Haplotype combinations of AdPLA gene polymorphisms associate with growth traits in Chinese cattle
Genetic variations of ANGPTL6 gene and their associations with growth traits and slaughter traits in
鲁西牛ANGPTL6基因的3个多态位点与其生长性状的关联性分析
哺乳类动物胃肠道内味觉受体的信号研究
A 5 '; UTR SNP of GHRHR locus is associated with body weight and average daily gain in Chinese cattl
Exploring polymorphisms of the bovine RARRES2 gene and their associations with growth traits
Exploring polymorphisms and associations of the bovine MOGAT3 gene with growth traits
Polymorphisms and effects on growth traits of the SH2B1 gene in Chinese cattle
SSR座位与秦川牛及其杂种牛生长性状的相关性分析
中国地方牛CCK基因第1外显子的多态性及其与生产性状的相关性
牛AMPK家族基因的研究进展
奶牛分子育种研究进展
核心蛋白多糖基因（DCN）的研究进展
郏县红牛SREBP-1c基因84 bp缺失突变的检测及其对6个生长性状的影响
基于mtDNA cytb基因变异的中国黄牛品种间遗传关系分析
OverlapPCR克隆黄牛脂肪特异性磷脂酶A2基因（AdPLA）及其原核表达
SDC3的功能及其研究进展
SH2B衔接因子蛋白l（SH2B1）研究进展
Single Nucleotide Polymorphism （SNP） Analysis of orexin Gene 5＇ Regulatory Region in Chinese Indigenous Cattle Populations
Novel 6-bp Deletion Mutation in visfatin Gene and Its Associations with Birth Weight and Bodyweight in Chinese Cattle
哺乳动物味觉感受器T1Rs受体家族及信号转导机制的研究进展
牛MRFs基因家族研究进展
南阳牛Gli3基因多态性及其与生长性状的相关性
秦川牛分子标记研究进展
牦牛分子标记研究进展
鸟枪法筛选枯草芽孢杆菌基因强启动子及对黄牛GHRL基因的表达
WNT信号通路的研究进展
grb14基因的功能及其研究进展
共激活因子PGC-1α的研究进展
水-甘油通道蛋白7基因（AQP7）的研究进展
短链脂肪酸受体GPR41、GPR43的信号通路及生理功能
期刊信息
  • 《中国牛业科学》
  • 主管单位:中华人民共和国教育部
  • 主办单位:西北农林科技大学 中国畜牧兽医学会养牛学分会 中国良种黄牛育种委员会
  • 主编：陈宏
  • 地址：陕西杨凌西北农林科技大学西农校区动物科技学院内
  • 邮编：712100
  • 邮箱：huangn2002813@aliyun.com
  • 电话：029-87091423
  • 国际标准刊号：ISSN：1001-9111
  • 国内统一刊号：ISSN：61-1449/S
  • 邮发代号:52-113
  • 获奖情况:
  • 全国中文畜牧学核心期刊,全国畜牧兽医优秀期刊,陕西省优秀科技期刊
  • 国内外数据库收录:
  • 英国农业与生物科学研究中心文摘
  • 被引量:2954