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WNT信号通路的研究进展
  • ISSN号：1001-9111
  • 期刊名称：《中国牛业科学》
  • 时间：0
  • 分类：S811.2[农业科学—畜牧学;农业科学—畜牧兽医]
  • 作者机构：[1]徐州师范大学细胞与分子生物学研究所,江苏徐州221116, [2]西北农林科技大学动物科技学院／陕西省农业分子生物学重点实验室,陕西杨凌712100
  • 相关基金：国家自然科学基金（30972080 31101703）; 江苏省自然科学基金（BK2011206）; 国家转基因重大专项（2009ZX08009-157B 2009ZX08007-005B-07）; 国家现代肉牛牦牛产业技术体系专项（CARS-38）项目资助
作者： 赵静[1], 张春雷[1], 房兴堂[1], 陈宏[1,2]
关键词： WNT信号, Β-CATENIN, 脂肪细胞, 通路, Wnt signaling pathway, β-catenin, adipose cell
中文摘要：

Wnt（wingless-type MMTV integration site family members）信号通路与细胞的发育分化密切相关,对正常和肿瘤细胞生长都至关重要,因其启动蛋白为Wnt蛋白而得名。本文综述了Wnt蛋白家族、Wnt信号通路、Wnt信号通路与疾病的关系以及WNT信号通路的研究进展,并对家族中一些成员的研究进行了展望。

英文摘要：

Wnt（wingless-type MMTV integration site family members） signaling pathway is closely related to cell development and differentiation,which is essential for normal and tumor cell growth.Because its promoting protein is Wnt protein,it named by Wnt protein.In this paper,the Wnt protein family,Wnt signaling pathway,the relationship between Wnt signaling pathway and disease,and research on Wnt signaling pathway are reviewed.At last,researches on some members of the family are prospected.

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期刊信息
  • 《中国牛业科学》
  • 主管单位:中华人民共和国教育部
  • 主办单位:西北农林科技大学 中国畜牧兽医学会养牛学分会 中国良种黄牛育种委员会
  • 主编：陈宏
  • 地址：陕西杨凌西北农林科技大学西农校区动物科技学院内
  • 邮编：712100
  • 邮箱：huangn2002813@aliyun.com
  • 电话：029-87091423
  • 国际标准刊号：ISSN：1001-9111
  • 国内统一刊号：ISSN：61-1449/S
  • 邮发代号:52-113
  • 获奖情况:
  • 全国中文畜牧学核心期刊,全国畜牧兽医优秀期刊,陕西省优秀科技期刊
  • 国内外数据库收录:
  • 英国农业与生物科学研究中心文摘
  • 被引量:2954