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哺乳动物味觉感受器T1Rs受体家族及信号转导机制的研究进展
  • ISSN号：1001-9111
  • 期刊名称：《中国牛业科学》
  • 时间：0
  • 分类：S823.2[农业科学—畜牧学;农业科学—畜牧兽医]
  • 作者机构：[1]徐州师范大学细胞与分子生物学研究所,江苏徐州221116, [2]西北农林科技大学动物科技学院,陕西省农业分子生物学重点实验室,陕西杨凌712100
  • 相关基金：江苏省高校自然科学基金（09KJD180002）; 国家高技术研究发展计划项目（编号：2006AA10Z197）; 国家自然科学基金项目（编号：30972080）; 转基因生物新品种培育科技重大专项项目（编号：2009ZX08009-157B 2008ZX08007-002）; 国家肉牛产业体系项目; 陕西省“13115”科技创新工程项目重点专项（2008ZDKG-11）资助
作者： 单俐敏[1], 张春雷[1], 陈宏[1,2], 房兴堂[1]
关键词： 味觉受体第一家族, 信号转导, 甜味识别, 鲜味识别, T1Rs, Signaling transduction, Sweet taste, Umami taste
中文摘要：

味觉受体第一家族（T1Rs）是一类能感知甜味和鲜味的受体家族,它包括T1R1,T1R2,T1R3三个成员。T1R2＋T1R3以异二聚体形式共表达参与甜味识别,而T1R1＋T1R3也以异二聚体形式共表达参与鲜味识别。良好的味觉能促进牛的食欲,促进生长发育,但目前关于牛的T1Rs受体家族的研究并不多见,有必要对这个受体家族做进一步探索。本文从甜味和鲜味两个方面对这一受体家族的分子结构及信号转导机制的最新研究进展做简要综述。

英文摘要：

The T1Rs receptors,a family of taste-specific class CG protein coupled receptors for sweet taste and umami taste,include T1R1,T1R2 and T1R3.T1R2＋T1R3 heterodimers mediate mammalian sweet taste.T1R1＋T1R3 heterodimers mediate mammalian umami taste.Good taste could promote the cattle＇s appetite and accelerate the growth and development.However,few research on bovine T1Rs receptors could be found.Therefore,it is essential for us to review the progress of T1Rs receptors.This paper reviews recent advances on the structure-function relationships of T1R receptors and signaling transduction mechanism from sweet taste and umami taste.

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期刊信息
  • 《中国牛业科学》
  • 主管单位:中华人民共和国教育部
  • 主办单位:西北农林科技大学 中国畜牧兽医学会养牛学分会 中国良种黄牛育种委员会
  • 主编：陈宏
  • 地址：陕西杨凌西北农林科技大学西农校区动物科技学院内
  • 邮编：712100
  • 邮箱：huangn2002813@aliyun.com
  • 电话：029-87091423
  • 国际标准刊号：ISSN：1001-9111
  • 国内统一刊号：ISSN：61-1449/S
  • 邮发代号:52-113
  • 获奖情况:
  • 全国中文畜牧学核心期刊,全国畜牧兽医优秀期刊,陕西省优秀科技期刊
  • 国内外数据库收录:
  • 英国农业与生物科学研究中心文摘
  • 被引量:2954