中文摘要：

目的：分析比较胃黏液腺癌（mucinous gastriccar cinoma,MGC）和印戒细胞癌（signet-ring cell carci-noma,SRC）的临床病理特征。方法：回顾性分析2002年-2014年我院及瑞金医院收治的59例MGC和75例SRC患者的临床病理资料。结果：MGC和SRC两组在发病年龄、肿瘤位置、肿瘤大体分型、浸润深度、临床TNM分期方面存在统计学差异（P〈0.05）。在性别比例、肿瘤切除部位、淋巴结转移数目及分期、淋巴管浸润、静脉浸润、神经浸润、远处转移方面无统计学差异（P〉0.05）。MGC组病例淋巴结转移率为67.8%,SRC组淋巴结转移率为54.7%（P〉0.05）。MGC较SRC更易出现远处转移,但无统计学差异（P〉0.05）。结论：MGC与SRC相比,发病年龄更大、肿瘤体积更大、胃上部多见、隆起型多见、进展期多见、远处转移多见。两者淋巴结转移率都很高,但无统计学差异,故临床发现MGC或SRC时,要更加注意有无淋巴结及远处转移,尤其是MGC。

英文摘要：

Objective：To compare the difference of clinicopathologic characteristics between mucinous gastric carcinoma（MGC） and signetring cell carcinoma（SRC）. Methods： Clinieopathological data of 59 patients with MGC and 75 patients with SRC from 2002 to 2014 in Xinhua hospital and Ruijin hospital were analyzed retrospectively. Resuits：There was significant difference in age, tumor location, macroscopic types, invasion depth and TNM stage between MGC and SRC （P 〈 0.05 ）. However, there was no significant difference in gender ratio, tumor excision site, lymph node metastasis,lymphatic invasion, venous invasion, perineural invasion and distant metastasis （ P 〉 0.05 ）. The rate of lymph node metastasis was 67.8% in MGC group and 54.7% in SRC group. MGC preferred more distant metastasis than SRC, but there was no significant difference（ P 〉 0.05 ）. Conclusion. Compared with SRC, MGC pre- fen＇ed to occur in older patients and the tumor size were larger. Carcinoma in upper third of stomach,protruded type, advanced stage and distant metastasis were more common in MGC patients. Both of their rates of lymph node metastasis were high, but there is no significant difference between them. For MGC or SRC clinically, more attention should be paid to the lymph node metastasis and distant metastasis,especially MGC patients.