目的观察臭氧治疗膝关节创伤性滑膜炎的临床疗效。方法 308例患者随机分成臭氧治疗组(n=156)和玻璃酸钠组(n=152),分别观察两组临床疗效、症状改善情况。结果①临床近期疗效比较:臭氧治疗组总有效率为91.67%,玻璃酸钠组总有效率为85.52%,两组总有效率比较,差异有统计学意义(χ2=9.984,P〈0.01);两组临床治愈率及显效率比较,差异也有统计学意义(χ2值分别为12.496和42.122,P〈0.01)。②两组症状改善比较:治疗2个疗程后,臭氧治疗组局部肿胀、局部疼痛及膝部活动受限积分比较,差异有统计学意义(P〈0.01)。③两组患者止痛时间及肿胀消退时间比较,差异有统计学意义(P〈0.01)。④远期疗效:两组不良反应及后遗症发生率比较,差异有统计学意义(P〈0.01)。结论臭氧治疗膝关节创伤性滑膜炎具有较好的临床疗效,是一种安全有效的新技术。
Objective To observe the clinical therapeutic effect of ozone on traumatic synovitis of knee joints.Methods 308 patients were divided into two groups randomly: the ozone treatment group(n=156) and the sodium hyaluronate treatment group(n=152).The clinical therapeutic effect and improvement of symptoms of the patients in both groups were observed respectively.Results ①Comparison of recent clinical therapeutic efficacy: the total effective rate of ozone treatment group was 91.67%;the total effective rate of the sodium hyaluronate treatment group was 85.52%.There was significant statistical difference between both groups in total effective rate(χ2=9.984,P0.01).There was significant statistical difference between both groups in clinical cure rate and markedly effective rate(χ2=12.49 and 42.12,P0.01).②Comparison of improvement of symptoms of both groups: after two courses of treatment,there was significant statistical difference between the scores of local swelling,local pain and limited knee mobility in the ozone treatment group(P0.01).③There was significant statistical difference between both groups in therapeutic efficacy on pain and swelling(P0.01).④Long-term therapeutic efficacy: there was significant statistical difference between both groups in terms of adverse reactions and occurrence rate of sequela(P0.01).Conclusion Ozone has a good therapeutic effect on traumatic synovitis of knee joints and is a safe and effective method.