中文摘要：

目的 了解镍接触人群胃癌病死率变化趋势,为制定胃癌防治策略提供科学依据。方法 收集2001—2010年镍接触人群的职工人数与胃癌死亡病例;计算胃癌粗病死率,以2000年甘肃省人口为标准计算标化病死率;计算其平均增长速度及年估计百分比变化（EAPC）,预测胃癌病死率。结果 2001—2010年职工共计432526人,10年因肿瘤死亡人数为925人,居死因顺位第一位。其中胃癌死亡172例,病死率为39.77/10万。男性和女性的标化病死率分别为30.15/10万、15.96/10万,男性胃癌病死率高于女性,差异有统计学意义（P〈0.05）。胃癌总病死率及男性病死率分别与年份呈正相关（r=0.841,P=0.002;r=0.823,P=0.003）,平均增长速度分别为9.42%和9.01%。男性、总胃癌EAPC分别为7.79%、8.65%;根据EAPC进行预测,结果显示,到2015年胃癌病死率分别增长至93.18/10万、71.81/10万。35岁以后胃癌病死率随着年龄的增加而升高,胃癌病死率在55岁以后呈迅速上升趋势,≥85岁达到高峰;65岁以前除45～岁组,各年龄组胃癌病死率增加,其中35～岁组增长606.21%;65岁以后胃癌病死率百分比均为负值。平均死亡年龄64.53岁。结论 镍接触人群胃癌病死率呈上升趋势,其中男性、高龄为胃癌的高危人群,应加强胃癌的预防与控制工作。

英文摘要：

Objective To obtain the gastric cancer mortality rate trend in an occupational population who has close contact with nickel in order to provide scientific data for the prevention and control of gastric cancer. Methods Data on people who had close contact with nickel and who died of gastric cancer from 2001 to 2010 were collected. The crude mortality rate of gas- tile cancer and the standardized mortality rate based on the population of Gansu province in 2000 were calculated. The average speed of growth and EAPC were also calculated to predict the mortality rate of gastric cancer. Results A total of 432 526 people were involved from 2001 to 2010. During the ten years, 925 people died of cancer, which was the first cause of death. 172 people died of gastric cancer with a mortality rate of 39.77 per 100 000. The standardized mortality rate of males and females were 30. 15 per 100 000 and 15. 96 per 100 000, and the gastric cancer mortality rate of males was significantly higher than the females. （P 〈 0. 05 ） . The overall mortality rate and mortality rate of males of gastric cancer were positively correlated with the years （ r = 0. 841, P =0. 002; r =0. 823, P =0. 003） , and the average speed of growth was 9.42% and 9.01% respectively. The EAPC of males and overall EAPC were 7.79% and 8.65% respectively. Based on the EAPC, it was predicted that by 2015, the mortal- ity rate of gastric cancer would reach 93.18 per 100 000 and 71.81 per 100 000 respectively. The mortality rate of gastric cancer increased with the ages, and increased rapidly after 55 years old, and reached its summit after 85 years old. Before 65 years old, except 45 years old group, the mortality rate all increased, with 35 years old group being 606. 21%. The mortality rate after 65 years old was negative value. Conclusion The gastric cancer mortality is seeing an increase, and the health problems of the male and old age workers should be paid more attention to.