目的 观察MMP9、hs-CRP、BNP、S-100和DD在急性缺血性脑卒中前的诊断价值.方法 选取入院时临床上怀疑AIS的患者99例,检测MMP9、hs-CRP、BNP、S-100和DD水平,以影像学的结果为金标准,探讨相应指标的诊断价值.结果 AIS组患者的MMP9、hs-CRP、BNP、S-100和DD明显升高,均值分别为(2.01±0.71) ug/L、(5.54±1.21) mg/L、(5.71±1.48) ng/L、(134.41±68.34) ng/L和(2.95±0.45) mg/L.临界值分别为0.15 ug/L、0.85 mg/L、0.66 ng/L、15.6 ng/L和0.35 mg/L.结论 MMP9和S-100对AIS具有诊断意义,该研究对于早期发现脑梗死前状态的患者具有重要意义.
Objective To discuss the diagnostic value of MMP9, hs-CRP, BNP, S-100 and DD in acute ischemic stroke patients. Methods 99 cases who was suspected for patients with AIS were selected, detect MMP9, hs-CRP, BNP, S-100 and DD, Imaging results was the gold standard to siscuss the siagnostic value of MMP9, hs-CRP, BNP, S-100 and DD in acute ischemic stroke patients. Results MMP9, hs-CRP, BNP, S-100 and DD of the AIS patients were significantly increased, the mean value was respectively(2. 01 ±0. 71 ) ug/L, (5.54±1.21) mg/L,(5.71 ±1.48) ng/L,(134.41 ±68.34) ng/L and (2.95 ±0.45) mg/L The diagnostic threshold were: 0. 15 ug/L, 0. 85 rag/L, 0. 66 ng/L, 15.6 ng/L and 0. 35 mg/L Conclusion MMI:'9 and S - 100 have higher diagnostic significance for AIS patients, the study has important significance for the early detec-tion of AIS.