在微波辐射下,离子液体催化苯乙酮或取代苯乙酮和N-溴代丁二酰亚胺(NBS)反应合成了7种α-溴代芳基酮,收率为73%~95%.最佳反应条件为:甲醇为溶剂,n(芳基酮)∶n(NBS)=1∶1,酸性离子液体MIM-PS-CH3SO3H为40 mol%,微波辐射功率为50或250 W.该反应时间短、产率高、环境友好、后处理方便、催化剂可重复使用.产物的结构经1H NMR,IR确证.
Seven α-bromoarylketones were obtained in yields of 73%~95% with ionic liquid as catalyst under microwave irradiation condition by the reaction of substituted acetophenones and N-bromosuccinim-ide.The optimal reaction conditions in methanol were as follows: n(aryl ketone)∶n(NBS)=1∶1,acidic ionic liquid MIM-PS-CH3SO3H was 40 mol%,microwave power was 50 or 250 W.The reaction easily could be worked up with short reaction time,high yields and environmental friendliness.The catalyst could be reusable.The products were identified by 1H NMR and IR spectra.