中文摘要：

目的系统评价丹红注射液治疗椎-基底动脉供血不足性眩晕的疗效与安全性。方法计算机检索CNKI、万方及维普数据库2007年1月至2014年12月丹红注射液治疗椎-基底动脉供血不足的随机对照试验（RCT）文献并手工检索相关期刊和会议论文,参照纳入与排除标准,并用Revman5.3软件进行Meta分析。结果符合纳入标准的文献共8篇共包含870名患者,方法学质量较低;Meta分析结果表明,在临床总有效率、临床痊愈率和临床显效率方面丹红注射液单独治疗椎-基底动脉供血不足的疗效是肯定的,在这8个随机对照试验中,没有不良反应出现。结论丹红注射液具有促进椎动脉血流速度改善、治疗椎-基底动脉供血不足性眩晕的作用,且安全性较高。然而因纳入研究质量低且样本量小,在不同程度上影响了上述结论的可靠性,故上述结论尚需进行设计合理、执行严格、多中心大样本且随访时间足够的随机对照试验进一步验证。

英文摘要：

Objective： To systematically assess the efficacy and safety of Danhong injection for the patients with VBI （Vertebra Basilar Insufficiency） compared with the compound salvia injection of the control group. Methods： Databases were electronically searched from CNKI, VIP, and Wanfang Data （January,2007 to December, 2014）, and reference lists of all papers identified according to the Cochrane Handbook for Systematic Reviews of Inter- ventions and evaluated by two assessors.RevmanS.3 were used to undertake Mata-analysis. Results： Eight trials involving 870 patients were included.,Meta-analysis showed that：Danhong injection was to be confirmed that it had a significant curative effect for VBI. No adverse reactions were reported in the 8 RCTs. Concluion： Danhong injection can effectively enhance the vertebral artery blood flow velocity,and appeared more curative and safer. Further high quality RCTs are required to provide reliable evidence on the treatment of the patients with VBI.