中文摘要：

目的了解射血分数正常心力衰竭的临床研究现状,为进一步临床研究提供参考。方法检索CNKI、万方、维普、PubMed、Embase、Cochrane等近10年文献,综合分析射血分数正常心力衰竭的临床研究现状。结果射血分数正常心力衰竭既往多称为舒张性心力衰竭,首次提出于1984年,距今已有30年,但对射血分数正常心力衰竭的研究相对较少,近10年来研究不断深入,但与射血分数降低(收缩性)心力衰竭相比,认识仍显不足。结论射血分数正常心力衰竭诊断标准仍不统一、病理生理机制仍不明确、治疗手段及用药仍无指南参考,多数药物治疗只能改善患者临床症状,对远期预后无影响,确定的证据尚需大样本、硬终点、长随访的临床试验进一步提供。

英文摘要：

Objective To understand the current conditions of clinical research of heart failure with normal ejection fraction,and to pro-vide reference for further clinical research.Methods Electronic search was done in CNKI,WangFang,VIP,Embase and Cochorane in ten years recently.The current situation of clinical research of heart failure with normal ejection fraction were analyzed.Results In 1984,investigator first proposed the idea that heart failure with normal ejection fraction had been cal ed diastolic heart failure for 30 years now.However,the study of heart failure with normal ejection fraction was not enough.In the past 10 years,even more and more studies focused on the heart failure with normal ejection fraction,it was insufficient to compare with heart failure with reduced ejection fraction (systolic heart failure). Conclusion The diagnostic criteria of heart failure with normal ejection fraction was not uniform. What’s more,the pathomechanism was stil unclear,and there was no guideline for treatment and medicine.Most of medicine just could improve the clinical symptom without effect on prognosis.Therefore,the study with large sample,completely mortality and com-posite endpoint and long fol ow up was needed to provide evidence to clinical research.