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中文摘要：
为发展新的手性配体，降低手性配体的合成成本，检验由芳醛与手性氨基酸酯缩合还原反应的普适性，以L-丝氨酸为手性源，经酯化，缩合，还原氨化，关环等反应，设计合成了一种新的茚满基氮杂环丙基二环丙基三级醇手性配体，其结构通过IR，1 H NMR，13 C NMR， HRMS进行了表征，发展了一条高效便捷合成这类具有光学活性化合物的方法。
英文摘要：
A novel Indancarbaldehyde chiral β-amino alcohol ligand has been successfully synthesized from readily available L -methionine through esterification , condensation , reductive alkylation , and further treatment with RMgX.This synthesis method is convenient and practical , which can be applied to industrialization .The structures of the target compound and the intermediates were confirmed by IR ,1 H NMR,13 C NMR, HRMS.
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