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中文摘要：
目的 研究毛冬青中木质素类化学成分。方法 采用硅胶柱色谱法、ODS柱色谱法、Sephedax LH-20柱色谱法、薄层色谱法及高效液相色谱法等方法对毛冬青体积分数70%乙醇提取物进行分离纯化,并根据理化性质及波谱数据鉴定分离得到化合物。结果 分离得到10个木脂素类化合物,经鉴定分别为（7R,7′R,7″R,8S,8′S,8″S）-4′,4″-dihydroxy-3,3′,3″,5-tetramethoxy-7,9′：7′,9-diepoxy-4,8″-oxy-8,8′-sesquineolignan-7″,9″-diol（1）、erythro-（7S,8R）-1-（4-hydroxy-3-methoxyphenyl）-2-{4-[（E）-3-hydroxy-1-propenyl]-2-methoxyphe-noxy}-1,3-propanediol（2）、erythro-（7R,8S）-1-（4-hydroxy-3-methoxyphenyl）-2-{4-[（E）-3-hydroxy-1-propenyl]-2-methoxyphe-noxy}-1,3-propanediol（3）、erythro-（7R,8S）-guaiacylglycerol-β-coniferyl aldehyde ether（4）、erythro-（7S,8R）-guaiacylglycerol-β-coniferyl aldehyde ether（5）、Vladinol D（6）、7S,8R-dihydrodehydroconiferyl alcohol（7）、（-）-丁香酯素[（-）-syringaresinol,8]、（-）-杜仲树脂酚[（-）-medioresinol,9]、（＋）-环橄榄树脂素[（＋）-cyclo-olivil,10]。结论 化合物1~7为首次从冬青属植物中分离得到。
英文摘要：
Objective To study the chemical constituents from Ilex pubescens Hook. Et Am.. Methods The compounds were isolated and purified by chromatographic methods such as silica gel, ODS, Sephadex LH- 20,TLC and HPLC from 70% ethanol extract of Ilex pubescens Hook. Et Am.. The structures were identified on the basis of physico-chemical properties and spectral data. Results Ten Ugnans were isolated. The structures of them were identified as （ 7R, 7＇ R, 7＂ R, 8S, 8＇ S, 8＂ S）-4＇, 4＂-dihydroxy-3,3＇, 3＂, 5- tetrarnethoxy-7,9＇ ： 7＇, 9-diepoxy-4, 8＂-oxy-8,8＇-sesquineolignan-7＂, 9＂-diol （ 1 ）, erythro-（ 7S, 8R ） -1 -（ 4- hydroxy-3-methoxyphenyl） -2- { 4-[ （E） -3-hydroxy-l-propenyl ] -2-methoxyphe-noxy } -1,3-propanediol （ 2 ）, erythro-（ 7R, 8S ）-1-（ 4-hydroxy-3-methoxyphenyl ）-2-{ 4-[ （ E ）-3-hydroxy-l-propenyl ]-2-methoxyphe- noxy / -1,3-propanediol （ 3 ）, erythro- （7R, 8S） -guaiacylglycerol-/3-coniferyl aldehyde ether （ 4 ）, erythro- （7 S, 8R）-guaiacylglycerol-fl-coniferyl aldehyde ether （5）, Vladinol D （6）, 7S, 8R-dihydrodehydroconiferyl alcohol （ 7 ）, （ - ）-syringaresinol （ 8 ）, （ - ） -medioresinol （ 9 ）, （ ＋ ）-cyclo-olivil （ 10 ）, respectively. Conclusions Compounds 1 -7 are obtained from genus Ilex for the first time.
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