中文摘要：

刚地弓形虫引起的弓形虫病是一种严重危害人类健康的人兽共患寄生虫病,采用疫苗防治该菌是当前研究的热点领域之一。SAG抗原是一种有效的疫苗候选分子,本文综述了乳酸乳球菌、耻垢分枝杆菌、鼠伤寒沙门氏菌、流产布鲁菌、根癌农杆菌、酵母菌、腺病毒、杆状病毒、假狂犬病毒、Ⅰ型猫疱疹病毒、新培斯病毒、A型流感病毒、蜥蜴利什曼原虫和犬新孢子虫等载体介导的刚地弓形虫SAG疫苗的研制现状。

英文摘要：

Toxoplasmosis caused by Toxoplasma gondii is a zoonotic parasitic disease that seriously endangers human health. Recent studies have focused on the use of vaccines to control this parasite. Surface antigens （SAGs） are molecules that could be effectively used to produce vaccines. This review outlines the status of research on vector-based SAG vaccines against T. gondii. These vectors include bacteria such as Lactococcus lactis, Mycobacteria smegrnatis, Salmonella typhirnuriurn , Brucella abortus , Agrobacterium turne f aciens , and Pichia Pastoris , viruses such as Adenovirus, Baculovirus, Pseudorabies virus, feline herpesvirus type 1, Sindbis virus, and influenza A virus, and parasites such as Leishmania tarentolae and Neospora caninurn.