经络效应的神经解剖基础是针灸机制研究热点之一,其效应主要取决于穴位、脊髓、脑针灸信息的产生、传导、整合与输出。神经示踪技术是神经生物学基本方法。该文介绍了近年来神经示踪技术在针灸领域应用进展,总结了针灸研究中应用的神经示踪剂种类、标记经络和腧穴相关神经元及其神经纤维在脊髓阶段和大脑区域性分布规律,为针灸效应神经生物学机制研究提供方法学参考.
The neuroanatomical basis of meridian effects is one of the focuses of acupuncture mechanism studies. Meridian effects depend mainly on the generation, conduction, integration and output of acupuncture information in the acupoint, spinal cord and brain.The neural tracer technique is a basic method in neurobiology. This article presents recent years' advances in the application of the neural tracer technique to acupuncture field and summarizes the types of neural tracer used in acupuncture studies and regularities in the distribution of neurons and their fibers related to labeled meridians and acupoints in spinal segments and brain regions to provide methodological reference for studies on neurobiological mechanism of acupuncture effects.