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中文摘要：
目的探究耳科常用实验动物内淋巴囊解剖位置及其异同,为临床内淋巴囊疾病发生发展机制研究提供解剖学依据。方法选取成年豚鼠、SD大鼠及KM小鼠,处死后取双侧颞骨和枕骨,明确内淋巴囊的位置及毗邻关系,然后将枕骨与颞骨分离,标定前庭导水管外口;解剖结果通过组织切片得以验证。结果 3种常用啮齿类实验动物内淋巴囊均在内听道后下方,在后半规管下方的骨盖外侧,其骨盖各不相同。豚鼠骨盖为一块薄骨板,大鼠骨盖为较长骨棘,小鼠骨盖为稍长骨棘,骨盖下都能见到前庭导水管外口;颞骨组织切片观察结果证实解剖位置就是内淋巴囊。结论 3种常用啮齿类动物内淋巴囊解剖位置大致相同,仅在解剖标志或组织形态上略有不同。
英文摘要：
Objective To explore the anatomical location of endolymphatic sac （ES） and its similarities and differences among common laboratory animals, in order to provide an anatomical basis for endolymphatic sac disease studies. Methods Adult guinea pigs, SD rats and KM mice were selected. The bilateral temporal and occipital bone were removed, and ES location and its adjacent landmarks were identified. Then the occipital and temporal bone were separated and vestibular aqueduct external aperture was marked. Histological sections were utilized for verification of our works. Results All endolymphatic sacs were located posteroinferior to the internal auditory canal and lateral to the bone cover beneath the posterior semicircular canal. Those bone covers showed different physical appearance in the three common laboratory rodents. The bone cover was a thin bone plate in guinea pigs, a long apophysis in SD rats, and a slightly longer apophysis in KM mice. Vestibular aqueduct external orifice could be seen under the bone cover clearly. It was verified with the histological section results. Conclusion The anatomical location of ES is roughly the same among the three common rodent animals, only anatomical marks or histomorphology shows slight differences.
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