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中文摘要：
以乙醛酸和苯酚为起始原料，在碱性溶液中经缩合反应得到对羟基扁桃酸钠，进一步经亚硫酸氢钠还原得到对羟基苯乙酸．目标产物经液相色谱进行了鉴定，结果表明，对羟基苯乙酸质量分数97．5％，纯度99．65％．研究发现：缩合反应中乙醛酸：苯酚：氢氧化钠的物质的量的比为1：1．5：2．5时，对羟基扁桃酸钠的收率可达85％；还原反应优化工艺：佗（对羟基扁桃酸钠）：竹（亚硫酸氢钠）=1：1．1，反应温度100℃，总压0．10～0．15MPa．该法原料来源广泛，工艺简单，成本低，产品质量好并且绿色环保，具有良好的工业前景．
英文摘要：
The target compound was obtained by condensation and reduction from phenol, 50% glyoxylic acid, and sodium bisulfite. The mass fraction and purity of 4-hydroxyphenyl acetic acid, determined by HPLC, were 97.5% and 99.65% respectively. The yield of sodium-4-hydroxyphenyl acetic acid reached 85% when the molar ratio of glyoxylic acid, phenol and sodium hydroxide was 1 ： 1.5 .： 2.5. The reductive reaction was performed at 100℃, under the pressure of 0. 10-0. 15 MPa, at 1 ： 1.1 molar ratios of sodium-4- hydroxymandalate monohydrate to sodium bisulfite. This method has a better industrial prospects by its extensive raw material, simple process, lower cost, better product quality and environmental protection.
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