中文摘要：

目的：观察补肾中药复方治疗老年性痴呆的临床疗效优势。方法：采用随机对照、双盲双模拟、多中心临床试验设计方法,将纳入的144例患者随机分为试验组和对照组每组72例,疗程为6个月,观察时间为0个月、3个月、6个月。结果：补肾复方中药与安理申均能改善患者MMSE、ADAS-cog、ADL量表评分,中药改善ADAS-cog评分优于安理申。分项研究,中药可改善＂延迟回忆、命令、口语能力＂评分,安理申可改善＂注意力和计算力、语言、单词辨认＂评分。疗效比较,中药改善＂单词回忆、单词辨认＂优于安理申,安理申改善＂语言＂评分可能优于中药,2组均能提高患者使用工具能力。结论：补肾复方中药能多方面改善患者认知功能及日常生活能力,较单靶点药物有一定的临床优势。

英文摘要：

Objective： Observing the clinical curative effect Tonifying kidney prescription for the treatment of mild alzheimer＇s disease advantage. Methods： The method of randomized,double-blind,double simulation,multicenter clinical trial were designed. Participants included 144 patients were randomly divided into trial group and control group,72 cases in each group,the treatment for 6 months,the observation time is 0 month,3 month,6month. Results： Tonifying kidney prescription and aricept can improve the patients＇ MMSE,ADAS- cog,ADL scale score,traditional Chinese medicine to improve ADAS- cog score better than aricept. Respective study： Chinese medicine can improve ＂ delayed recall,command,speaking ability score; Aricept can improve the attention and computing power,language and word recognition ＂ score. On the aspect of Clinical curative effect,Chinese medicine＇s improving ＂ the word memory,identify ＂ is better than aricept,aricept improve＂language＂score may be better than the traditional Chinese medicine. Both groups can improve the ability of patients using tools. Conclusion： Traditional Chinese medicine can improve the patients＇ cognitive function and daily life ability in many aspects.