目的了解负性生活事件与高血压和空腹血糖受损之间的关系。方法随机整群抽样选取安徽省六安市3个乡镇18个行政村40~70岁村民进行入户面询问卷调查,邀请完成问卷调查的村民于次日清晨去村卫生室检测指端末梢血糖(空腹〉8 h)并测量2次平均血压(静坐时间〉30 min,间隔时间≥15 min)。采用logistic回归分析高血压和空腹血糖受损与负性生活事件、年龄、性别、文化程度、吸烟指数、每日酒精摄入量和体质指数之间的关系。结果不同年龄、性别、吸烟指数、每日酒精摄入量、体质指数、负性生活事件指数的村民高血压患病率差异有统计学意义(P〈0.05);不同年龄、性别、文化程度、体质指数、负性生活事件指数的村民空腹血糖受损率差异有统计学意义(P〈0.05);logistic回归分析结果显示,年龄(OR=0.35~0.66)、性别(OR=1.81)、文化程度(OR=1.21)和体质指数(OR=1.20)是高血压患者患病的影响因素,而负性生活事件对高血压的影响无统计学意义;文化程度(OR=0.77~0.72)、每日酒精摄入量(OR=1.64)、体质指数(OR=1.07)和负性生活事件(OR=1.32~1.80)是空腹血糖受损的影响因素。结论负性生活事件与空腹血糖受损密切相关,应注重构建生活事件干预理论,以指导人们采取积极的态度应对负性生活事件。
Objective To explore the impacts of stressful life events on hypertension and impaired fasting glucose among rural adults. Methods We selected residents aged 40- 70 years from 18 villages in three tow nships using random cluster sampling and employed a questionnaire to collect information on demographics,stressful life events,and living behaviors of the participants by trained medical graduates with a face-to-face interview. Next day after the interview,we determined the participants' fasting capillary plasma glucose( FCG) using glucose meters and blood pressure derived from two consecutive measurements( at least 10 minutes apart) taken from the right arm after sitting still for at least 30 minutes using standard mercury sphygmomanometers. We adopted logistic regression to analyze the associations between hypertension,impaired fasting glucose and stressful life event,age,sex,education,smoking index,alcohol consumption,and body mass index( BM I). Results There were significant differences in the prevalence of hypertension and FCGamong the participants of different age,gender,smoking index,alcohol consumption per day( only for hypertension),BM I,and stressful life event index( all P〈0. 05). Logistic regression analyses revealed that hypertension was significantly related to age( odds ratio[OR]= 0. 35- 0. 66),gender( OR = 1. 81),education( OR = 1. 21),and BM I( OR = 1. 20) and impaired FCGwas significantly related to education( OR = 0. 77- 0. 72),alcohol consumption per day( OR = 1. 64),BM I( OR =1. 07),and stressful life events index( OR = 1. 32- 1. 80). Conclusion Stressful life events are closely associated with impaired fasting glucose and life event intervention theory should be constructed to guide people to cope with stressful life event among rural adults.