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云南松松塔水部位对豚鼠离体回肠的影响
  • ISSN号:1007-8517
  • 期刊名称:《中国民族民间医药杂志》
  • 时间:0
  • 分类:R285.5[医药卫生—中药学;医药卫生—中医学]
  • 作者机构:[1]大理大学,云南大理671000, [2]保山中医药高等专科学校,云南保山678000
  • 相关基金:国家自然科学基金项目(NO:81260632);云南省自然科学基金项目(NO:2012FD036).
中文摘要:

目的:初步探讨云南松松塔水部位对豚鼠离体回肠的活性。方法:观察云南松松塔水部位对正常和阿托品或苯海拉明预收缩豚鼠离体回肠的影响。结果:云南松松塔水部位终浓度在300~1200μg/mL之间可以使豚鼠正常离体回肠平滑肌的张力和面积均明显增大;终浓度大于300μg/mL的云南松松塔水部位可以使苯海拉明诱导下豚鼠离体回肠平滑肌的张力和面积均有所增大;云南松松塔水部位对阿托品诱导下豚鼠离体回肠平滑肌无影响。结论:在一定剂量范围内,云南松松塔水部位对豚鼠离体回肠有兴奋作用,其机制可能与M受体有关,与H受体无关。

英文摘要:

Objective To study the effects of water extracts from Yunnan pine cone on isolated ileum in guinea pig. Methods To observe the effects of different concentrations of water extracts from Yunnan pine cone on the contraction of normal isolated ileum or atropine or diphenhydramine induced contracted isolated ileum. Results The water extracts from Yunnan pine cone at the final concentration of 100 μg/mL to 300 μg/mL could enhance the tension and the area of normal isolated ileal smooth muscle in guinea pigs; The water extracts from Yunnan pine cone at the concentration of 300 μg/mL could enhance the tension and the area of isolated ileal smooth muscle after diphenhydramine in guinea pigs; The water extracts from Yunnan pine cone had no effect on isolated ileal smooth muscle after atropine. Conclusion In certain dose, the water extract from Yunnan pine cone could stimulate isolated ileum of guinea pigs, and the responding mechanism may be related to the M receptor but not the H receptor.

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期刊信息
  • 《中国民族民间医药杂志》
  • 主管单位:云南省科学技术协会
  • 主办单位:云南省民族民间医药研究会
  • 主编:郑进
  • 地址:昆明市关威远街166号龙园A座
  • 邮编:650201
  • 邮箱:zgyy1992@163.com
  • 电话:0871-65349183 5339255
  • 国际标准刊号:ISSN:1007-8517
  • 国内统一刊号:ISSN:53-1102/R
  • 邮发代号:64-56
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:32488