目的了解老年支气管哮喘病人控制现状及影响因素。方法选择在南京医科大学第一附属医院呼吸与危重症医学科门诊就诊的哮喘病人,记录病人一般资料、评估哮喘控制水平以及哮喘控制测试评分(asthma control test,ACT)、了解哮喘管理包括医生制定的哮喘随访计划、药物的使用情况等,应用Logistic回归分析与ACT评分相关的影响因素。结果有150例哮喘病人完成了问卷调查,根据"全球哮喘倡议"(GINA)的标准,老年哮喘病人的完全控制、部分控制和未控制的比例分别为27.3%、45.5%、和27.3%。老年哮喘病人的ACT评分为(20.2±4.2)分。老年哮喘病人较非老年者合并高血压、冠心病、睡眠呼吸暂停低通气综合征比例高(P〈0.05)。将所有对象分为ACT≥20分及〈20分组,是否使用糖皮质激素吸入剂或含有糖皮质激素的吸入制剂对老年病人的ACT评分有显著影响(P〈0.05),而非老年哮喘病人中过去一年是否急诊就诊是影响ACT评分的重要因素(P〈0.05)。结论是否使用吸入性糖皮质激素是影响老年哮喘病人ACT评分的独立影响因素之一。
Objective To investigate the control status and influencing factors of bronchial asthma in the elderly patients.Methods The patients with asthma were selected in the outpatient Department of Respiratory and Critical Care Medicine of the First Affiliated Hospital of Nanjing Medical University.The clinical data of patients were recorded,and the control status of asthma was assessed.The follow-up plans and drug use were recorded,Logistic regression analysis was used to analyze the influencing factors of control level.Results 150 patients completed the questionnaire survey.According to the Global Asthma Initiative(GINA) standards,the overall control,partial control and uncontrolled control rate of elderly patients with asthma was 27.3%,45.5%,and 27.3% respectively.The asthma control test(ACT) score of elderly patients with asthma was 20.2±4.2.Elderly patients with asthma were more likely to suffer from hypertension,coronary heart disease and sleep apnea-hypopnea syndrome than nonelderly patients(P〈0.05).Using glucocorticoid inhaler or an inhaled formulation containing glucocorticosteroidshada have significant effect on ACT scores in elderly patients(P〈0.05).Conclusions Whether using glucocorticoid inhaler or an inhaled formulation containing glucocorticosteroids is an independent influencing factor for ACT scores in elderly patients with asthma.