位置:成果数据库 > 期刊 > 期刊详情页
联用技术研究生物体中硒化学种态的发展趋势
  • 期刊名称:光谱学与光谱分析. 26 (12). 2354-2359, 2006
  • 时间:0
  • 分类:O657[理学—分析化学;理学—化学]
  • 作者机构:[1]中国科学院高能物理研究所核分析技术重点实验室,北京100049
  • 相关基金:国家自然科学基金“十五”重大项目(10490180)和中国科学院重要方向性项目(KJCX2-N101)资助
  • 相关项目:重金属汞和稀土的毒理
中文摘要:

环境和生物体中硒的含量极低,化学种态(Chemical species)非常复杂,使其种态分析十分困难。如何选择性测定元素硒的特定种态,从而更好地理解它在体内的代谢以及在生理学、毒理学、营养学、临床化学等方面的重要意义是非常具有挑战性的工作,这些都依赖于现代分析技术的发展。文章重点评述了现代联用技术的现状和发展趋势,尤其是适用于元素物种选择性测定的分离方法和检测硒化合物的鉴定方法。

英文摘要:

In the environment and living organisms, limited concentrations and complexity of selenium compounds constitute challenges to the analytical techniques. Since their biological activities are dependent on their chemical states and structure, the key issue lies in the .selective determination of the particular species of selenium, which is beneficial to clearly understanding its biochemical roles in metabolism, physiology, toxicology, nutrition, and clinical chemistry. For these purposes, the advanced analytical techniques are greatly indispensable. In the present paper, the current status and development trends in the speciation analysis of selenium by hyphenated techniques is selectively reviewed with the emphasis on the coupling of electrophoretic or chromatographic separation with atomic spectroscopy and mass spectrometry, which render element-selective detection and identification of selenium compounds.

同期刊论文项目
期刊论文 104 会议论文 70
同项目期刊论文