中文摘要：

用NADPH-黄递酶组织化学方法对15日龄、4月龄和12月龄山羊小肠肌间神经丛中NOS阳性神经元形态和分布进行了比较研究。结果显示，山羊小肠肌间神经丛中NOS阳性神经元和阳性神经纤维形成清晰的三级网状结构，NOS阳性神经元形态各异，聚集在一起构成大小不等的神经节。神经丛中NOS阳性神经元的密度随年龄增长而降低，3个年龄段（从小到大）分别为27．07、20．80、16．18个／mm^2；神经元总数增加，分别为1．86×10^6、4．06×10^6、4．41×10^6个；在各个年龄小肠NOS阳性神经元密度均以空肠较低，神经元总数在各年龄均以空肠最多；山羊小肠肌间神经丛NOS阳性神经元胞体面积、胞核面积发育前期增加，后期减小；核质比随年龄下降，15日龄与4月龄和12月龄之间差异显著（P〈0．05）．小肠不同肠段的NOS神经元胞体、胞核面积分布随年龄出现一定变化，相同年龄小肠各段神经元核质比差异不显著（P〉0．05）。

英文摘要：

Using NADPH-diaphorase histochemistry staining, the morphology and distribution of the nitric oxide synthase （NOS） positve neurons in myenteric plexus of goat small intestine were studied at 15 days,4 months and 12 months of age. The results showed that the NOS positive neurons in myenteric plexus of goat small intestine and NOS positive nerve fibers formed clearly a three-class reticular formation. The shapes of NOS positive neurons were different, and lots neurons gathered together, coming into some different size ganglia. With the goats growing,from 15 days to 12 months of age the density of NOS positive neurons in the plexus decreased （about 27.07,20.80 and 16.18 neuron/mm^2 respectively）, but the total number increased （about 1.86 × 10^6 ,4.06× 10^6 ,4.41× 10^6 respectively）. The neurons density in the jejunum of different ages was the lower, but the number was the highest. The mean somatic area and nuclear area of the neurons enlarged firstly and then decreased with goat growing, and the mean ratio between nuclear and plasmic area decreased with growing. There was a notable difference between 15 day-age and 4 month-age, 15 day-age and 12 month-age goat（P〈0.05）. The mean somatic and nuclear of the neurons from the duodenum to the ileum showed differences, but the mean ratio between nuclear and plasmic area had no notable difference（P〉0.05）.