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中文摘要：
大肠埃希菌能够引起鸡大肠杆菌病，对养殖业危害巨大。检测阜新某鸡场分离的33株鸡源大肠埃希菌对6种临床常用的四环素类药物的敏感性，并对四环素耐药基因进行检测。结果表明，大肠埃希菌分离株对土霉素和脱氧土霉素高度耐药；对四环素和多西环素中度耐药；对金霉素和强力霉素敏感。在33株大肠埃希菌分离株中检测出tetB、tetC、tetM、tetK、tetI。5种四环素耐药基因，未检出tetA基因，tetK检出率最高。
英文摘要：
E. coli could cause chicken colibacilosis and bring huge harm to breeding industry. In this study, 33 E. coli isolates were obtained from a chicken breeding farm in Fuxin area, and antibiotic sensitivity test was taken out to detect the sensitivity of isolates to 6 kinds of tetracyclines which commonly used in clinical treatments. And drug resistance genes were screened. The results showed that, isolates were highly resist- ant to oxytetracycline and doxycyclinum, moderately resistant to tetracycline and doxycylcline, and sensitive to duomycin and deoxytetracycline. 5 kinds of resistance genes were screened in 33 E. coli isolates, the positive genes were tetB,tetC,tetM,tetK and tetL,none isolates was positive for tetA gene,and tetK was the major resistance gene.
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