龙葵碱主要存在于茄科植物马铃薯(Solanum tuberosum)的块茎及龙葵(Solanum nigrum)的全草中。近年研究发现,龙葵碱除具有毒性作用外,还具有抗肿瘤、抗病原微生物作用。国内外学者对其药理、毒理作用及机制进行了深入研究。本文对龙葵碱药理学和毒理学研究相关进展进行综述,为其进一步的研究和应用提供参考。
Solanine mainly exist in the tubers of Solanum tuberosum and in the whole herb of Solanum nigrum. In recent years, the studies shows that solanine has anti-tumor and antimicrobial activities except for its toxic effect. Domestic and foreign scholars have con-ducted deep studies on the pharmacological and toxic effects and the mechanisms of solanine. This article reviews the research progress in Pharmacology and toxicology research of solanine, which will provide references for its further research and application.