中文摘要：

目的了解沈阳地区皮肤癣菌病致病菌的构成和变迁。方法对中国医科大学附属第一医院皮肤科门诊1984年1月至2007年12月皮肤癣菌培养资料进行回顾性分析，并与张致中总结的该地区此前20年（1954～1963年，1974-1983年）的皮肤癣菌培养结果进行对比。结果共分离出致病菌株3792株，位列前3位的致病菌依次为红色毛癣菌（2369株、62．4％）、须癣毛癣菌（903株、23．8％）、犬小孢予菌（280株、7.3％），同张致中的报道相比，须癣毛癣菌（23．8％ vs 16．9％）和犬小孢子菌（7．3％ vs 0.3％）比例上升。结论沈阳地区皮肤癣菌病致病菌的优势菌株为红色毛癣菌。1984—2007年的统计结果同1954—1963年加1974-1983年的统计结果相比，致病菌发生了变迁。

英文摘要：

Objective To identify epidemiological trends and the predominant organisms causing superficial fungal infections in Shenyang region. Methods This was a retruspective analysis of dermatophyte infections based on data from the mycology laboratory coveting the period from 1984 to 2007 at the Department of Dermatology Outpatient Service,The First Hospital Affiliated to China Medical University. All the positive fungal cultures were studied, the proportions of dermatophytosis and their causing organisms were calculated. Comparisons were made between the data of dermatophytosis from 1984 to 2007 and the data of the past 20 years previously reported by Zhang Zhizhong. Results There were total 3792 strains of pathogenic species isolated. The first three causal agents isolated were Trichophyton rubrum （2369/62.4%）, Trichophyton mentagrophytes（903/23.8% ）and Microspomm canis（280/7.3% ）. Compared to the report by Zhang Zhizhong,the incidence of Trichophyton mentagrophytes had increased（23.8% vs 16.9%）,so had that of Micmsporum canis（7.3% vs 0.3%）. Conclusion Trichophyton rubmm remains the predominant pathogenic species of dermatophytosis in Shenyang region. Statistical results indicate that there has been a change in the composition of pathogenic organisms.