目的:探讨光动力与红、蓝光照射治疗面部痤疮的临床效果。方法:选取本院皮肤性病门诊收治的92例面部痤疮患者随机分为试验组和对照组各46例,试验组采用光动力疗法,对照组采用红、蓝光治疗,两组患者均治疗8个周。结果:治疗前,试验组和对照组粉刺、丘疹、脓疱、结节囊肿个数、GAGS评分差异均无统计学意义(P〉0.05),治疗8周后,试验组的粉刺、丘疹、脓疱、结节囊肿数目、GAGS评分显著的少于或低于对照组(P〈0.05),试验组的愈显率84.78%显著地高于对照组的65.22%(P〈0.05),试验组有的总有效率97.83%与对照组的93.48%差异无统计学意义(P〉0.05)。试验组的不良反应率10.87%与对照组的23.91%差异无统计学意义(P〉0.05)。结论:光动力治疗面部痤疮的效果优于红、蓝光照射的治疗效果,同时不良反应发生率较少。
Objective To investigate the clinical efficacy of photodynamic therapy with red and blue light in the treatment of facial acne. Methods Ninety-two cases of facial acne in dermatology outpatient hospital were randomly divided into the test group and the control group, with 46 cases in each group. Patients in the test group received the photodynamic therapy, and patients in the control group received red plus blue light treatment for eight weeks, respectively. Results Before treatment, patients in the test group and the control group had no significant differences in acne, papules, pustules, nodules, cysts and gags score. After 8-week treatment, the comedones,papules, pustules, nodules cyst number, gags score of patients in the test group were significantly less than or lower than those of patients in the control group(P 0.05, respectively). The healing rate was 84.78% in the test group, which was higher than that of 65.22% in the control group of(P 0.05). The total efficiency was 97.83% in the test group and 93.48% in the control group, with no significant difference. The adverse reaction rate was10.87% in the test group and was 23.91% in the control group, with no significant difference. Conclusion The effect of photodynamic therapy for facial acne is better than red plus blue light treatment,with a less incidence of adverse reactions.