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Symptom clustering in chronic gastritis based on spectral clustering

ISSN号：0255-2922
期刊名称：Journal of Traditional Chinese Medicine
时间：2014.8.15
页码：504-510
分类：S858.28[农业科学—临床兽医学;农业科学—兽医学;农业科学—畜牧兽医] O212.4[理学—概率论与数理统计;理学—数学]
作者机构：[1]Basic Medical College, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China, [2]Center for Mechatronic Engineering, East China University of Science and Technology, Shanghai 200237, China
相关基金：Supported by the National Natural Science Foundation of China[the Patterns Differentiation Mode of Main TCM Clinical Symptoms Based on Complex System Method（No.81270050）; Information Extraction From TCM Inquiry and the Deducting Method of Patterns Differentiation Based on Feature Selection（No.30901897）; Common Syndrome Diagnosis of Traditional Chinese Medicine Based on The Integration of Four Diagnosis Methods（No.81173199）]; College Students＇ Scientific Innovation Foundation of Shanghai University of TCM[SHUTCMCXHDZ（2011）03]; the Foundation for Training Talents of National Basic Scientific Research（No.J1103607）
相关项目：中医学专业本科生科研创新能力训练体系建设与优化

关键词：慢性胃炎, 聚类分析, 症状, 脾胃虚寒, 集群, 特征选择, 聚类算法, 医学理论, Gastritis Cluster analysis Pattern Symptom complex

中文摘要：

OBJECTIVE: Apply spectral clustering to analyze the patterns of symptoms in patients with chronic gastritis(CG).METHODS: Based on 919 CG subjects, we applied mutual information feature selection to choose the positively correlated symptoms with each pattern.Then, we used the Shi and Malik spectral clustering algorithm to select the top 20 correlated symptoms.RESULTS: We ascertained the results of six patterns.There were three categories for the pattern of accumulation of damp heat in the spleen-stomach(0.00332). There were six categories for the pattern of dampness obstructing the spleen-stomach(0.02466). There were two categories for the pattern of spleen-stomach Qi deficiency(0.013 89).There were three categories for the pattern of spleen-stomach deficiency cold(0.009 15). There were five categories for the pattern of liver-Qistagnation(0.01910).There were four categories for the pattern of stagnant heat in the liver-stomach(0.00585).CONCLUSION: Most of the spectral clustering results of the symptoms of CG patterns were in accordance with clinical experience and Traditional Chinese Medicine theory. Most categories suggested the nature and/or location of the disease.

英文摘要：

OBJECTIVE： Apply spectral clustering to analyze the patterns of symptoms in patients with chronic gastritis（CG）.METHODS： Based on 919 CG subjects, we applied mutual information feature selection to choose the positively correlated symptoms with each pattern.Then, we used the Shi and Malik spectral clustering algorithm to select the top 20 correlated symptoms.RESULTS： We ascertained the results of six patterns.There were three categories for the pattern of accumulation of damp heat in the spleen-stomach（0.00332）. There were six categories for the pattern of dampness obstructing the spleen-stomach（0.02466）. There were two categories for the pattern of spleen-stomach Qi deficiency（0.013 89）.There were three categories for the pattern of spleen-stomach deficiency cold（0.009 15）. There were five categories for the pattern of liver-Qistagnation（0.01910）.There were four categories for the pattern of stagnant heat in the liver-stomach（0.00585）.CONCLUSION： Most of the spectral clustering results of the symptoms of CG patterns were in accordance with clinical experience and Traditional Chinese Medicine theory. Most categories suggested the nature and/or location of the disease.

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