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中文摘要：
目的：明确香菇、辣椒、带鱼、羊肉和海虾5种食物对慢性变应性接触性皮炎（CACD）小鼠模型炎症反应及血清 IL-4和 IL-17表达的影响。方法：36只小鼠用2，4-二硝基氟苯诱导建立CACD 模型，5种食物煎煮后灌胃，对照组予纯水灌胃。测量每组耳厚度和耳重量并用 ELISA 检测血清 IL-4和 IL-17水平。结果：与对照组相比，辣椒和羊肉明显增加耳厚度、耳重量和血清 IL-17水平（P〈0.05）；带鱼和海虾对小鼠耳厚度和耳重量无明显影响（P〉0.05），但显著下调血清 IL-4水平（P〈0.05）；香菇对各项指标均无影响（P〉0.05）。结论：辣椒和羊肉可能通过上调血清 IL-17水平加重CACD 小鼠模型炎症反应。
英文摘要：
Objective： To determine the effects of mushroom, chillies, ribbonfish, mutton and sea shrimp on contact dermatitis in mice model. Methods： The contact dermatitis model was constructed by DNFB. The mice were divided into 5 groups and fed with the soup of 5 foods by gavage and the mice in control group were fed with water. Ear thickness and weight were measured. The levels of IL-4 and IL-17 in serum were detected by ELISA. Results： Compared with control group, the ear thickness and weight, and the levels of IL-17 were increased in the chillies group and mutton group（P〈0.05）. There was no changes in ear thickness and weight in ribbonfish and sea shrimp group, but the level of IL-4 decreased（P〈 0.05）. There were no significant differences in the ear thickness and ear weight changes, and the serum levels of IL-4 and IL-17 between mushroom group and control group （P〉0.05）. Conclusion： Chillies and mutton may aggravate the inflamma-tory reaction in contact dermatitis by upregulating IL-17 expression.
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