目的 探讨Neuroform EZ支架构建“Y”形支架辅助弹簧圈栓塞颅内分叉部宽颈动脉瘤(WNBA)的临床疗效及其优势.方法 回顾性分析首都医科大学附属北京天坛医院神经介入科2016年10月至2017年3月应用Neuroform EZ支架构建“Y”形支架辅助弹簧圈栓塞治疗6例WNBA患者的临床资料.所有患者术中行数字减影血管造影,采用Raymond评分评估动脉瘤的即刻栓塞效果.术后30 d行临床随访,随访内容为改良Rankin量表评分(mRS).结果 6例患者手术操作成功率为100%,无操作相关并发症发生.术中DSA显示6个动脉瘤均完全栓塞,Raymond评分为Ⅰ级.术后2例患者出现脑梗死,其中1例给予补液、肝素抗凝治疗后病情好转出院;另1例给予肝素抗凝治疗后未出现神经功能缺失症状.术后30 d随访,6例患者的mRS评分为0~1分.结论 双Neuroform EZ支架或Neuroform支架联合其他颅内自膨支架构建“Y”形支架辅助弹簧圈栓塞是治疗WNBA安全有效的方法,但远期疗效有待于进一步研究.
Objective To evaluate the clinical effects and advantages of Neuroform EZ in constructing Y configured stent in the treatment of wide necked bifurcation aneurysm (WNBA).Methods Retrospective data was retracted regarding 6 cases of WNBA treated with Neuroform EZ in a Y configuration from October 2016 to March 2017 at Department of Interventional Neuroradiology,Beijing Neurosurgical Institute,Beijing Tiantan Hospital,Capital Medical University.Intraoperative DSA was performed in all cases and immediate results of embolization were assessed based on Raymond scale.Clinical follow-up was conducted at 30 days post surgery based on modified Rankin scale.Results The success rate of operation in 6 patients was 100% without surgery-related complications.Intraoperative DSA indicated complete embolization in 6 aneurysms which were classified as grade Ⅰ according to Raymond scale.Postoperative cerebral infarction occurred in 2 cases including 1 reporting symptomatic relief following fluid infusion and heparin anticoagulant therapy before discharge and the other undergoing heparin anticoagulant therapy and developing no neurological deficits at discharge.All patients had the mRS score of 0-1 assessed at the follow-up 30 days post surgery.Conclusion Y-configuration double-stent-assisted coiling,using either 2 Neuroform EZ stents or 1 EZ and some other stent,could be important and effective in treatment of WNBA.But the long-term curative effect remains to be further research.