中文摘要：

本研究提取251头大白母猪毛囊基因组，以PCR—RFLP法对繁殖性状候选基因FSH—β（促卵泡素β亚基）、ESR（雌激素受体）和BF（备解素因子）进行基因分型和遗传效应分析。结果表明：该猪群3个基因的优势等位基因分别为B、B和A；初产母猪FSH书基因的AB基因型健仔数和初生窝重分别比AA型多1．21头和1．60kg（P〈0．05），经产母猪AB和BB型初生窝重比AA型分别多1．42妇和1．24kg（P〈0．05）；BF基因的AA型初产母猪出生窝重高出AB型母猪1．54kg（P〈0．05）；FSH书、ESR、BF的优势合并基因型为ABAAAA，含此基因型母猪的全仔数、健仔数、初生窝重比最低的AAABAA型母猪分别高1．44、1．45、2．21奴（P〈0．01）；个体育种值估计结果表明，ABAAAABBAAAA等合并基因型母猪的全仔数及健仔数排名该猪群前10名。本试验结果为大白猪繁殖性状的分子标记辅助选择提供了参考。

英文摘要：

To study the molecular basic of sow reproduction traits of 251 Yorkshire, three SNPs in swine follicle stimulating hormoneβ（FSH-β）, estrogen receptor （ESR） and properdin （BF） genes in pig hair follicle genome were genotyped by PCR-restriction fragment length polymorphisms （PCR-RFLP） techniques. The effects and relationships of the three SNPs with the reproductive traits in the Yorkshire population were analyzed. The dominant gene frequency for FSH-β, ESR and BF in the population were B, B and A, respectively. At the first parity, the sows with AB genotype in FSH-β gene had significantly higher number healthy birth （NHB） and litter birth weight （LBW） than AA （1.21 heads and 1.60 kg） （P〈0.05）. As for the multiparity, the sows with AB and BB genotypes of FSH-β gene showed significantly higher LBW than the AA sows （1.42 kg and 1.24 kg） （P〈0.05）. The sows with AA genotype of BF gene was found increased 1.54 kg LBW than the AB sows （P〈0.05）. The sows with combined genotype of AB AA AA for FSH-~, ESR and BF genes was found significantly higher total number birth （TNB）, NHB and BLW than the AA AB AA sows （increased 1.44 heads, 1.45heads and 2.21 kg, respectively） （P〈0.01）. Besides, the estimated breeding value （EBV） for TNB and NHB showed that the sows with AB AA AA, BB AA AA are listed in the top ten in the population. The study results provide the basic molecular information for improvement of swine reproduction traits.