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中文摘要：
利用模拟移动床结合离子交换法从酶转化液中连续分离L-苯丙氨酸。在模拟移动床分离过程中，L-苯丙氨酸的吸附波稳定在区Ⅲ，吸附损失为零，单位质量树脂对L-苯丙氨酸的吸附量可达到125g／kg树脂，提高了树脂利用率；利用区Ⅰ的解吸尾流解吸杂质，L-天冬氨酸、蛋白等杂质的解吸波稳定在区Ⅱ，先于L-苯丙氨酸脱离模拟移动床分离系统；L-苯丙氨酸在区Ⅰ被集中解吸，解吸液中L-苯丙氨酸的浓度达35g／L。实验结果表明该法的L广苯丙氨酸解吸收率达97．6％，单位质量L-Phe的氨水（0．5mol／L）消耗率仅为38．37L／kg。
英文摘要：
A new separation method of L-phenylalanine （L-Phe） from liquid of transformation was studied, and based on ion exchange and continuous separation by simulated moving bed （SMB） with standing wave design. The results showed that adsorption wave of L-Phe stays in zone Ⅲ without any adsorption loss, and the adsorptive capacity of L-Phe is 125g/kg resin, whereas the utilization of resin is improved. Desorption waves of asparagic acid and protein stay in zone Ⅱ by wake flow of the extract from zone Ⅰ and desorption wave of L-Phe stays in zone Ⅰ. The L-Phe concentration of elution is above 35g/L, while 97.6% L-Phe is obtained from desorption by simulated moving bed with ammonia consumption （0.5mol/L） rate of L-Phe only 38.37L/kg.
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