目的:观察喉癌淋巴管的微细分布和超微结构特征,为探讨喉癌淋巴转移机理提供形态学依据。方法:采用半薄切片光镜观察、超薄切片电镜观察人喉癌组织中央区、周边区和正常区内淋巴管的形态学变化。结果:喉癌中央区未见淋巴管,周边区淋巴管数量较正常区明显增多,管腔扩大;毛细淋巴管管壁破坏,细胞器发生明显改变。正常区毛细淋巴管的形态和超微结构未见明显改变。结论:喉癌淋巴管的分布及形态的改变与肿瘤细胞经淋巴道转移密切相关。
To observe the morphology of lymphatics in Laryngocarcionma by providing the morphologic data for the study of the molecular mechanism of tumor metastasis. Methods: Lymphatics in center, peripheral and normal regions of human Laryngocarcionma samples were observed by means of semithin sections under light microscope and uhrathin sections under electron microscope. Results:There were no lymphatics in carcinomatous center region. Compared with normal region, there were more initial lymphatics in peripheral region of Laryngocarcionma. The lumina were dilated and the capillaries were destroyed. The organelle changed obviously. The distribution and morphology were changed evidently in the normal region. Conclusion: The morphologic change of the distribution and in the tumor lymphic vessels have close relation to lymphatic metastasis.