肿瘤患者常有情志不遂、心情低落等气郁的临床表现,认为气机郁结在肿瘤发生发展中具有重要作用。应以理气解郁为主要治法,包括理气疏肝解郁、理气消痰解郁、理气活血解郁、理气清热解郁,其机制可能与诱导肿瘤细胞凋亡、抑制肿瘤细胞增殖、调节免疫、逆转肿瘤细胞的多药耐药性有关。
The cancer patients often feel depressed or manifest with other symptoms caused by qi stagnation. Therefore, qi stagnation is an important cause of cancer. Qi-rectifying depression-resolving therapy is commonly used in cancer treatment, including qi-rectifying liver-soothing and depression-resolving therapy, qi-rectifying phlegm- dispersing and depression-resolving therapy, qi-rectifying blood-quickening and depression-resolving therapy and qi- rectifying heat-clearing and depression-resolving therapy. The mechanism of action may be related to inducing tumor cell apoptosis, inhibiting tumor cell proliferation, regulating immune, and reversing multidrug resistance of tumor cells.