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中文摘要：
【目的】探讨佛山地区低钾性周期性麻痹患者的职业特点及中医证型特点。【方法】采用多中心回顾性方法分析佛山地区本病发病人群的职业特点及中医证型特点,并探讨二者间的相关性。【结果】（1）职业分布：本病发病最常见于农林牧渔劳动者及生产运输工人,分别为36.8%和34.7%。（2）证型分布：最常见证型为湿热证,占53.1%;其次为气虚证和气阴两虚证,分别占20.3%和15.7%。（3）证型分布与职业关系：农林牧渔劳动者、生产运输工人及军人等重度体力劳动者的中医证型均以湿热证为最多,分别为62.5%、69.4%和47.0%;专业技术人员的中医证型以气阴两虚证为最多,占44.4%;商业服务低钾性周期性麻痹是急诊科较常见的危急重症之一,多见于青壮年男性,发作时以四肢松弛性瘫痪为主,严重时可出现呼吸肌麻痹、严重的心律失常而危及生命。该病属中医＂痿病＂范畴。痿病是指肢体筋脉弛缓、软弱无力,日久因不能随意运动而致肌肉萎缩的一种病证[1]。现有的研究显示该病的发生与钾离子代谢息息相关[2],但其发病机制未明,国外报道认为此病常有家族史,而在我国多以散发为主。目前,国内对于该病的好发职业人群及中医证型特点研究较少。本课题采用多中心回顾性研究方法,分析佛山地区具有代表性的4家医院2010年10月至2015年8月所收治的782例低钾性周期性麻痹患者的职业特点及中医证型分布特点,现将研究结果报道如下。业人员的中医证型以气阴两虚证和气虚证为主,分别为32.5%和31.3%;重度体力劳动者的中医证型与其他轻体力劳动、脑力劳动者比较,差异有统计学意义（P〈0.001）。【结论】佛山地区低钾性周期性麻痹的职业高发人群为重度体力劳动者,其证型多为湿热证,而在轻体力劳动及脑力劳动者的发病人群中多为气虚证及气阴两虚证。
英文摘要：
Objective To investigate the distribution of occupations and traditional Chinese medical syndromes of the patients with hypokalemic periodic paralysis in Foshan area. Methods A multicenter retrospective investigation was carried out to analyze the characteristics of occupations and syndrome types of hypokalemic periodic paralysis in Foshan area, and the correlation of occupations with syndrome types was also explored.Results（1）The workers engaged in agriculture,forestry,animal-breeding and fishing,and the workers engaged in production transportation were most likely to suffering from hypokalemic periodic paralysis, with the incidence being 36.8%, 34.7% respectively.（2） The damp-heat syndrome was the most commonly-seen syndrome type,accounting for 53.1%,and then followed by Qi deficiency syndrome（20.3%） and Qi-Yin deficiency syndrome（15.7%）.（3） The syndromes of heavy manual labor workers such as agriculture,forestry,animal-breeding and fishing workers,production transportation workers, and soldiers were characterized by damp-heat type, accounting for 62.5%, 69.4%, 47.0% respectively. Professionals technicians were most likely to suffering from Qi-Yin deficiency syndrome, accounting for 44.4%; business service personnel were most likely to suffering from Qi-Yin deficiency syndrome（32.5%） and Qi deficiency syndrome（31.3%）. The syndrome distribution of heavy manual labor workers differed from that of light manual labor workers and brain workers（P〈0.001）. Conclusion The high-risk groups of hypokalemic periodic paralysis in Foshan area are the heavy manual labor workers who are manifested with the damp-heat syndrome. The dominated syndrome types of light manual labor workers and brain workers are Qi deficiency and Qi-Yin deficiency.
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