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表面微纳米结构对细胞的影响
  • ISSN号：1671-6264
  • 期刊名称：东南大学学报(医学版)
  • 时间：2011
  • 页码：190-200
  • 分类：Q2[生物学—细胞生物学] O63[理学—高分子化学;理学—化学]
  • 作者机构：[1]聚合物分子工程教育部重点实验室,复旦大学高分子科学系,上海200433
  • 相关基金：国家重大科学研究计划资助项目（2009CB930000）;国家自然科学基金资助项目（21034002）
  • 相关项目：细胞与材料相互作用的基本科学问题研究
作者： 彭荣|丁建东|
关键词： 生物材料, 微纳米结构, 细胞, 拓扑, 图案, 文献综述
中文摘要：

在再生医学材料研究中,细胞与材料相互作用是一个基本问题,其中材料表面的微观结构对细胞的生物调控作用是重要内容之一。具有表面化学结构和几何拓扑结构的基底是用来研究细胞的行为和功能的有效手段。将细胞的黏附配体选择性地修饰到材料表面,从而能在空间上定位细胞,研究细胞的特定行为和功能,比如黏附、增殖、极化、迁移和分化等。另外用几何拓扑结构的图案可调控细胞的各种行为和功能,比如用各向异性的条纹拓扑结构来研究细胞的＂接触引导＂行为等。本文从表面化学结构和几何拓扑结构两方面概述了微纳米结构对细胞行为的调控这一领域的研究工作。

同期刊论文项目
　面向组织修复与替代的纳米生物材料的研究
期刊论文 45
细胞与材料相互作用的基本科学问题研究
期刊论文 150 会议论文 85 获奖 5
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期刊信息
  • 《东南大学学报：医学版》
  • 中国科技核心期刊
  • 主管单位:教育部
  • 主办单位:东南大学
  • 主编：唐萌
  • 地址：南京市鼓楼区丁家桥87号
  • 邮编：210009
  • 邮箱：bjb@pub.seu.edu.cn
  • 电话：025-83272481
  • 国际标准刊号：ISSN：1671-6264
  • 国内统一刊号：ISSN：32-1647/R
  • 邮发代号:28-265
  • 获奖情况:
  • 全国优秀学报,铁道部优秀期刊
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,波兰哥白尼索引,中国中国科技核心期刊,中国北大核心期刊（2014版）
  • 被引量:8241