生物材料的生物相容性是生物材料研究领域的关键科学问题。分子生物学技术的发展使生物材料的生物相容性评价从动物水平和细胞水平深入到分子水平。生物组学技术的发展为高通量进行生物材料分子生物相容性评价、阐明生物材料与生物体的相互作用机理提供了有效的手段。本文综述了生物材料生物相容性研究现状及基因组学、蛋白质组学技术在生物材料生物相容性研究中的应用。
Biocompatibility is a key scientific issue in the research area of biomaterials. With the development of molecular biology techniques, the evaluation of biocompatibility of biomaterials has deepened from the animal level and cellular level to molecular level. The development of biomics technologies provide effective tools for high-throughput evaluating molecular biocompatibility on whole scale, and understanding the interaction mechanism between biomaterial and human body. In this paper, current research of biocompatibility and the application of biomics technologies in biocompatibility study of biomaterials were reviewed.