中文摘要：

目的研究Ⅰ期手术治疗结肠穿孔的有效性及安全性。方法将綦江区人民医院胃肠外科2011年9月至2014年4月收治的37例结肠穿孔患者分为观察组与对照组。观察组行Ⅰ期穿孔修补术或肠切除吻合术;对照组行分期手术,Ⅰ期行穿孔修补术或肠管切除术,Ⅱ期行近端肠管造瘘术。比较两组患者的疗效及安全性。结果两组患者术中出血量、切口感染发生率、心肺并发症发生率及住院时间比较,差异无统计学意义（P〉0.05）;观察组患者术后肛门排气、排便时间大于对照组,住院费用高于对照组,组间比较差异均有统计学意义（P〈0.05）。所有患者均安全度过围术期,无严重并发症发生,观察组19例患者中发生术后吻合口瘘1例、切口感染3例、无腹腔感染发生。结论对部分结肠穿孔患者行Ⅰ期手术治疗安全有效,值得临床推广。

英文摘要：

Objective To research the efficacy and safety of the one-stage operation for treating colonic perforation.Methods 37 cases with colonic perforation in our department from Jan.2013 to Apr.2014 were divided into the observation group and the control group.The observation group was preformed the one-stage operation,including perforation repairing or intestinal resection and anastomosis;the control group was performed the operation by stages,the stageⅠ was performed the perforation repairing and the stageⅡ was performed the proximal intestinal fistulation.The effects and safety were compared between the two groups.Results The intraoperative bleeding volume,incision infection rate,occurrence rate of cardiopulmonary complications and hospitalization time had no statistical differences between the two groups（P〉0.05）;the anal exsufflation time and defecation time in the observation group were greater than those in the control group,the hospitalization costs were higher than those in the control group,the differences showed statistical significance（P〈0.05）.All cases safely spent the perioperative period without serious complication occurrence.Among 19 cases in the observation group,1case of anastomotic fistula and 3cases of incision infections occurred.No peritoneal infection happened.Conclusion Conducting the one-stage operation in partial patients with colonic perforation could be safe and effective and deserves to be promoted in clinic.