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中文摘要：
目的研究危重病患者血清乳酸（LacticAcid）与血PH值变化的临床意义及与预后的关系。方法回顾性总结132例急诊ICU患者，血清乳酸、PH值与碱剩余（BE）的水平，根据乳酸水平将患者分为4组。分析乳酸水平在不同状态下，与血PH值与碱剩余（BE）的关系及死亡率的变化。结果132例危重患者有85例血清乳酸升高，占总数的64．39％，血Lac增高组死亡率明显高于血Lac正常组（P〈0．01）；血Lac水平愈高，预后愈差，死亡率愈高。血Lac〉12，死亡率明显增高（P〈0．001）。同时显示：血Lac水平与PH值呈负相关，血Lac水平愈高，PH值愈低。相关系数-0．8738，P〈0．001。结论危重病患者中，血LAC测定有助于了解组织细胞的缺氧情况。血LAC浓度的变化与血PH变化有良好相关性，血LAC的变化可以反映病情变化，它是判定预后的一个重要指标。
英文摘要：
Objective To study the clinical significance and prognosis value of blood lactic acid and pH for critical ill patients. Methods A retrospective review strategy was used to analyze the blood lactic acid, pH and the base excess （BE） levels of 132 patients in emergency intensive care unit. The patients were divided into four groups according to the blood lactic acid level. Correlation between the blood lactic acid level and pH, BE was compared at different state. The mortality of different groups was also compared at different state. Results： Among the observed 132 patients, there were 85 cases （64.39%） with high blood lactic acid level. The mortality of high lactic acid level group was higher than the normal group （P 〈 0.01 ）. The higher the lactic acid level, the poorer the progress, and also the higher the death rate. The mortality was significantly increased as the lactic acid level was higher than 12 （P〈 0.001 ）. There was negative correlation between the lactic acid level and pH. The higher the lactic acid level, the lower the pH （correlation coefficient-0.8738, P〈0.001）. Conclusions Blood lactic acid level provides useful information to learn about the anoxemia condition in, tissue and cells. There is significant correlation between the lactic acid level and pH. The blood lactic acid level could be a useful reflection for ill state, which also would be an important index for prognosis evaluation.
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