目的:观察益心泰治疗急性心肌梗死的临床疗效及对醛固酮(Aldsterone,ALD)水平的影响。方法:将符合纳入标准的60例急性心肌梗死患者随机分为治疗组和对照组各30例,两组均给予常规心肌梗死治疗,治疗组在常规治疗基础上加用益心泰治疗,每次10g,口服,每天3次,6周为1个疗程,观察1个疗程后比较两组疗效、心电图的改善、心脏彩超的变化、酶学检查以及ALD水平的变化情况。结果:两组治疗6周后的临床症状和客观指征均明显改善,治疗组优于对照组(P〈0.05)。结论:益心泰可以降低急性心肌梗死惠者ALD水平,阻止心室重构。
Objective: To observe the therapeutic efficacy of Yixintai in the treatment of acute myocardial in-farction and the effect of Yixintai on aldosterone (ALD) level. Methods: Sixty patients with acute myocardial in-farction were randomly divided into treatment group ( n=30 ) and control group ( n = 30). Both group received conventional therapy for myocardial infarction. Additionally, each patient in the treatment group was orally given Yixintai 3 times (10 g each time) every day for 6 weeks (one period of treatment). The two groups were compared with respect to therapeutic efficacy, electrocardiogram improvement, ultrasonic cardiogram change, enzyme exami-nation results, and ALD level. Results : After 6 weeks of treatment, both groups showed significant improvement in clinical symptoms and the above indices, and the treatment group was significantly better than the control group in these tients regards ( P 〈 O. 05 ). Conclusion : Yixintai can decrease ALD level and inhibit ventricular remodeling in pa-with acute myocardial infarction.