从环境的化学信号的识别和感觉为有机体的幸存是很重要的。在哺乳动物,一般化学信号被主要嗅觉的系统(瞬间) 主要检测,当 pheromones 被 vomeronasal 系统(VNS ) 首先察觉时。Pheromones 是个人在一样的种类以内释放并且认出的化学药品,它然后在社会、性的活动导致生理、行为的变化。在这评论,我们在哺乳动物的 vomeronasal pheromone 感觉在研究上集中于最近的进展,对 vomeronasal 唯一的那些基因部件表明 transduction 小径,包括象短暂受体潜力隧道 2 基因( TRPC2 )一样的 vomeronasal 受体 V1R 和 V2R 基因家庭,试着使哺乳动物的 pheromone 感觉的分子的机制的进一步的学习清楚些。
The recognition and perception of chemical signals from environments are very important for the survival of organisms. In mammals, general chemical signals are mainly detected by the main olfactory system (MOS), while pheromones are primarily perceived by the vomeronasal system (VNS). Pheromones are chemicals released and recognized by individuals within the same species, which then induce physiological and behavioral changes in social and sexual activities. In this review, we focus on the recent advances on research in mammalian vomeronasal pheromone perception and those genetic components unique to vomeronasal signal transduction pathway, including vomeronasal receptor V1R and V2R gene families as well as transient receptor potential channel 2 gene (TRPC2), trying to shed light on further study of the molecular mechanisms of mammalian pheromone perception.