黄曲霉毒素(AF)是一种真菌毒素,广泛存在于各种饲料原料中。黄曲霉毒素B1(AFB1)是毒性最强的一种AF,常污染奶畜饲料。在动物体内,AFB1氧化代谢成黄曲霉毒素M1(AFM1),AFM1可分泌到奶畜乳中。本文综述了AF的理化性质、有害生物学效应与机制、生物转化及其向奶畜乳、尿液、粪便和组织转移的规律。
Aflatoxins( AF) is a mycotoxin and occur naturally in many feedstuffs. Aflatoxin B1( AFB1),the most toxic compound of aflatoxins,and a common occurrence in dairy animal feeds. In animal body,aflatoxin M1( AFM1) is oxidative metabolite of AFB1 and can carry over to dairy animal milk. In this paper,physical and chemical properties,adverse biological effects and mechanism,biological transformation of AF in milk,urine,feces and tissues in dairy animals were reviewed.