欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
先天性心脏病（cHD）是人类最常见的出生缺陷，也是婴幼儿死亡的首要原因。其具体的发病机制至今仍未完全清楚，但已证实其病因主要为环境因素、遗传因素以及两者的共同作用。CHD患者较普通人群更易出现染色体异常，其中最常见的是21-三体综合征，18-三体综合征，少部分的CHD患者的染色体异常为结构异常，主要表现为缺失、重复。本文就CHD与染色体异常的关系作一综述。
英文摘要：
Congenital heart disease （CHD） is the most common birth defect, which is the leading cause of death in infants and young children. Its specific pathogenesis is still not entirely clear, but has been con- firmed that the main causes were environmental factors, genetic factors, as well as a combination of both. CHD is more frequent in patients with congenital heart defects than in the general population. Down syndrome, trisomy 18 syndrome are common ones. A few chromosome abnormality in patients with CHD are structural abnormalities, such as deletion, duplication. We reviewed the relationship between the CHD and chromosome abnormality.
同期刊论文项目
同项目期刊论文
期刊信息
位置：