中文摘要：

目的：系统评价针灸与西药比较治疗高脂血症的疗效和安全性。方法：计算机检索CBM、CNKI、VIP和WanFang Data,检索时限至2014年4月,纳入针灸（针刺、电针、温和灸、氦-氖激光穴位针法）与西药（普伐他汀片、辛伐他汀、非诺贝特、洛伐他汀）比较治疗高脂血症的临床随机对照试验（RCT）。由2位研究人员根据纳入与排除标准独立进行文献筛选、数据提取、质量评价,由第3人进行核对,分歧文献由第3人裁定。采用Rev Man 5.2软件进行Meta分析。结果：共纳入9个RCT,733例患者,Meta分析结果显示：（1）LDL-C降低值,针灸组优于药物组[MD=1.05,95%CI（0.86,1.25）,P〈0.00001];（2）TC降低值,药物组优于针灸组[MD=-0.31,95%CI（-0.46,-0.15）,P〈0.0001];（3）TG降低值,针灸组优于药物组[MD=0.62,95%CI（0.45,0.79）,P〈0.00001];（4）HDL-C升高值,针灸组优于药物组[MD=0.62,95%CI（0.45,0.79）,P〈0.00001];（5）总有效率,针灸组与药物组对于高脂血症均有效,无明显差异[OR=1.26,95%CI（0.90,1.77）,P=0.18]。结论：基于当前临床证据,针灸治疗高脂血症患者的疗效在降低LDL-C和TG水平以及提高HDL-C的水平方面优于药物组。

英文摘要：

Objective： To systematically assess the effectiveness and safety of acupuncture and moxibustion for the treatment of hyperlipidemia. Methods： Databases including CBM,CNKI,VIP and Wanfang were electronically searched from inception to Apr.2014 for the randomized controlled trials（ RCTs） on acupuncture and moxibustion（ manual acupuncture,electroacupuncture,He-Ne laser acupoint needling method） versus drugs（ pravastatin,simvastatin,lovastatin fenofibrate） for hyperlipidemia. Two reviewers independently screened literature according to the inclusion and exclusion criteria,extracted data and assessed the methodological quality of the included. The third researcher checked the results and ruled the literature which the two reviewers had different comments on. And then,the Meta- analysis was performed using Rev Man 5. 2 software. Results： In total,9 RCTs and 733 patients were included. The results of Meta- analysis indicated：（ 1） Acupuncture and moxibustion group＇ s effects on decreasing LDL- C was better than that of the drugs group[MD = 1. 05,95% CI（ 0. 86,1. 25）,P 〈0. 00001].（ 2） Drugs group＇s effects on decreasing TC was better than that of the acupuncture and moxibustion group[MD =- 0. 31,95% CI（- 0. 46,- 0. 15）,P 〈0. 0001].（ 3）Acupuncture and moxibustion group＇ s effects on decreasing TG was better than that of the drugs group[MD = 0. 62,95% CI（ 0. 45,0. 79）,P 〈0. 00001].（ 4） Acupuncture and moxibustion group＇s effects on decreasing HDL- C was better than that of the drugs group[MD = 0. 62,95% CI（ 0. 45,0. 79）,P 〈0. 00001].（ 5） Acupuncture and moxibustion and drugs groups were both effective for hyperlipidemia and there was no significant difference between two groups[OR = 1. 26,95% CI（ 0. 90,1. 77）,P =0. 18]. Conclusion： Based on current clinical evidence,for hyperlipidemia,the effectiveness of acupuncture and moxibustion was better than the drugs＇,except the decreasing of TC value. And the safety of acupuncture and moxibustion was be