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灸药结合治疗虚性小儿哮喘非急性发作期的临床疗效及对IgE、EOS、LTE4含量的影响
  • ISSN号:1004-745X
  • 期刊名称:《中国中医急症》
  • 时间:0
  • 分类:R272[医药卫生—中医儿科学;医药卫生—中医学]
  • 作者机构:[1]湖南旺旺医院,湖南长沙410000, [2]湖南中医药大学第一附属医院,湖南长沙410007, [3]湖南中医药大学,湖南长沙410007
  • 相关基金:国家重点基础研究973计划项目(2009CB522904); 国家自然科学基金课题资助(81173326); 长沙市科技计划重点项目(K1005020~31)
中文摘要:

目的比较艾条温和灸、灸药结合、中药治疗虚性非急性发作期小儿哮喘患者的临床疗效观察,探讨灸药结合治疗虚性小儿哮喘的临床疗效及其可能的作用机理。方法 90例患儿按病情分层抽样的实验设计原则分为艾灸组、灸药结合组和中药组,每组各30例。艾灸组采用单纯艾条温和灸,每穴灸10 min,每日1次。中药组以口服平喘方为主,每日1剂,2~3次温服。灸药组的艾灸方法及穴位同艾灸组,中药处方及服用方法与中药组相同。疗程均为2个月。分别于治疗前、后各记录1次疗效指标,检测血清总免疫球蛋白E(IgE)含量、外周血嗜酸性粒细胞(EOS)直接计数、尿白三烯E4水平。结果灸药组的临床总有效率明显优于其他2组(P〈0.05)。3种疗法均能有效地降低患儿血清总IgE含量、外周血EOS直接计数及尿LTE4含量,其中以灸药结合组效果最佳。结论单纯艾条温和灸及口服中药治疗虚性小儿哮喘非急性发作期均有较好的疗效,而艾条温和灸与中药结合运用,临床效果则更突出。

英文摘要:

Objective: To observe the clinical effect of deficient children asthma in non-acute phase treated by the moxa stick mild-ward moxibustion(MWM),the moxibustion medication(MM) combined and the Chinese medicine and to explore the clinical effect and the effective mechanism of moxibustion medication combined.Methods: 90 cases were divided into 3 groups at experimental design principle of stratifily sampling by the condition of asthma such as the MWM group,the MM combined group and the Chinese medicine group with 30 cases in each group.The MWM group was only given moxa stick mild-ward moxibustion with 10 minutes every acupoint each time.The Chinese medicine group was only taken orally Pingchuan Decoction with one dose every day.The MM combined group was given the same moxbustion methods in the MWM group.The treatment of each group was lasted 2 months.Then the effect guideline and determine the levels of IgE,EOS and LTE4 were observed respectively before and after therapy.Results: The total effective rate of the MM combined group was higher obviously than that in other groups.Levels including IgE,EOS and LTE4 in 3 groups were imprvoed significantly.Moreover,the improvement of the MM combined group was the best of these groups.Conclusion: The results of research shows that the effect of MWM or Chinese medicine treating deficient children asthma in nonacute onset stage is valid.The MM combined is the validest of all.

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期刊信息
  • 《中国中医急症》
  • 中国科技核心期刊
  • 主管单位:国家中医药管理局
  • 主办单位:中华中医药学会
  • 主编:晁恩祥
  • 地址:重庆市江北区盘溪七支路6号
  • 邮编:400021
  • 邮箱:zgzyjzyx@126.com
  • 电话:023-67064128 63521390
  • 国际标准刊号:ISSN:1004-745X
  • 国内统一刊号:ISSN:50-1102/R
  • 邮发代号:78-98
  • 获奖情况:
  • 全中中医药优秀期刊三等奖
  • 国内外数据库收录:
  • 中国中国科技核心期刊
  • 被引量:45864